Evidence map›Paper›PMID 34001654›Full record

ArticleOpen heart2021

Improvements of predictive power of B-type natriuretic peptide on admission by mathematically estimating its discharge levels in hospitalised patients with acute heart failure.

Eiji Anegawa, Hiroyuki Takahama, Kunihiro Nishimura, Daisuke Onozuka, Yuki Irie, Kenji Moriuchi, Masashi Amano, Atsushi Okada, Makoto Amaki, Hideaki Kanzaki and 4 more

Open access · goldAbstract read
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Eiji AnegawaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.ORCID 0000-0003-1534-4431
Hiroyuki TakahamaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan takahama@cardio.med.tohoku.ac.jp.ORCID 0000-0003-4155-1936
Kunihiro NishimuraDepartment of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Daisuke OnozukaDepartment of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.ORCID 0000-0001-9596-9188
Yuki IrieDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Kenji MoriuchiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Masashi AmanoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Atsushi OkadaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.ORCID 0000-0002-0087-4168
Makoto AmakiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Hideaki KanzakiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Teruo NoguchiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.ORCID 0000-0001-5372-4932
Kengo KusanoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.ORCID 0000-0002-5760-9285
Satoshi YasudaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Chisato IzumiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
National Cerebral and Cardiovascular Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsEarlier studies showed that in patients with heart failure (HF), circulating levels of B-type natriuretic peptide (BNP) at hospital discharge (BNP

methodsWe identified patients admitted to our hospital for HF (BNP

resultsThrough stepwise regression of the patient data (n=688, New York Heart Association 3-4, 88%), we found age, blood urea nitrogen and eLVEDP to be significantly (p<0.05) associated with BNP

conclusionThis study showed that statistically accounting for confounding factors affecting BNP levels improves the predictive power of BNP levels measured at the time of hospital admission, suggesting that these confounding factors are associated with lowering predictive power of BNP on admission. TRIAL REGISTRATION NUMBER: UMIN 000034409, 00035428.

Indexed as

InpatientsModels, TheoreticalPatient AdmissionPatient DischargeAcute DiseaseAgedAged, 80 and overBiomarkersCross-Sectional StudiesFemaleHeart FailureHumansMaleNatriuretic Peptide, BrainPredictive Value of TestsRetrospective StudiesBiomarkersNatriuretic Peptide, Brainbiomarkersdiastolicheart failuresystolic Pl

Identifiers

PMID34001654
PMCPMC8130754
OpenAlexW3160782612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.