Evidence map›Paper›PMID 34001621›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB.

Aidin R Balo, Alessio Caruso, Lizhi Tao, Dean J Tantillo, Mohammad R Seyedsayamdost, R David Britt

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Biosynthesis of Macrocyclic Peptides by Formation and Crosslinking ofbioRxiv : the preprint server for biology · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. In situ ligand-modulated activation of inert Ce(III/IV) into ozonation catalyst for efficient water treatment.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Reversible Alkyl-Group Migration between Iron and Sulfur in [FeJournal of the American Chemical Society · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aidin R BaloDepartment of Chemistry, University of California, Davis, CA 95616.ORCID 0000-0003-0967-6683
Alessio CarusoDepartment of Chemistry, Princeton University, Princeton, NJ 08544.ORCID 0000-0001-5612-8140
Lizhi TaoDepartment of Chemistry, University of California, Davis, CA 95616.
Dean J TantilloDepartment of Chemistry, University of California, Davis, CA 95616.
Mohammad R SeyedsayamdostDepartment of Chemistry, Princeton University, Princeton, NJ 08544; mrseyed@princeton.edu rdbritt@ucdavis.edu.ORCID 0000-0003-2707-4854
R David BrittDepartment of Chemistry, University of California, Davis, CA 95616; mrseyed@princeton.edu rdbritt@ucdavis.edu.ORCID 0000-0003-0889-8436
University of California, Davis · USPrinceton University · US

Funding

Supplement:Spectroscopy Investigations of Metalloenzyme MechanismsR35GM126961 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI R. David Britt · 2018 to 2026
$3.7M
NIGMS NIH HHS R35 GM126961
6 · The paper itself

Abstract

The radical

Indexed as

Bacterial ProteinsBinding SitesCatalysisCloning, MolecularElectron Spin Resonance SpectroscopyEscherichia coliGene ExpressionGenetic VectorsIron-Sulfur ProteinsKineticsLysineModels, MolecularOxidation-ReductionProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandBacterial ProteinsIron-Sulfur ProteinsLysineRecombinant ProteinsRibosomal ProteinsS-AdenosylmethionineTryptophanbiochemistrybioinorganic chemistrychemical biologyenzymologyEPR spectroscopy

Identifiers

PMID34001621
PMCPMC8166192
OpenAlexW3160089421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.