ArticleClinical medicine (London, England)2021
Treatment of spontaneous intracranial hypotension: experiences in a UK regional neurosciences Centre.
Article in Clinical medicine (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Targeted Versus NonTargeted Epidural Blood Patch for Spontaneous Intracranial Hypotension: A Systematic Review and Meta-Analysis.European journal of neurology · 2025Pooled it
- Spontaneous epidural blood patch at T2/3 with resolution of intracranial hypotension.Surgical neurology international · 2026Article
- A Low-Volume Epidural Blood Patch for the Treatment of Spontaneous Intracranial Hypotension: A Case Report.Cureus · 2024Article
- Management of cervical CSF-venous fistula causing acute cognitive impairment and coma.Acta neurochirurgica · 2024Article
- Intracranial hypotension in a breast cancer patient treated with epidural blood patches.CNS oncology · 2023Article
- Treatment, Outcome, and Relapse of Spontaneous and Nonspontaneous Cerebrospinal Fluid Leak.Brain sciences · 2022Article
- Survey of healthcare professionals' knowledge, attitudes and practices regarding spontaneous intracranial hypotension.BMJ neurology open · 2022Article
- Successful management of spontaneous intracranial hypotension with epidural blood patch.BMJ case reports · 2021Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A robust treatment paradigm for spontaneous intracranial hypotension has yet to be agreed upon. We present retrospective data from the patient cohort at our UK regional neurosciences centre from 2010-2020 and describe our locally developed treatment pathway.Seventy-three patients were identified: 31 men and 42 women; mean age was 42 years. The majority presented with a headache of variable duration, and most had positive imaging. Very few patients (7%) responded to conservative treatment. Sixty-six underwent epidural blood patching, with 39 (59%) having a good response. Twenty-three patients underwent myelography and targeted treatment (injection of fibrin sealant at the leak site), with 13 (57%) showing a good response. One patient had successful surgery. The relapse rate after response to epidural blood patching was 10%, and after response to targeted treatment was 23%. Most patients who relapsed responded to repeated treatments.The outcome data for our diverse patient cohort shows the success of a staged approach to treatment. Relapse rates are low, and surgery is only rarely required. We use these data to inform our discussions with patients, and present them here to enable other centres to develop robust investigation and treatment paradigms of their own.
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