Evidence map›Paper›PMID 34001292›Full record

ArticleEpidemiology and infection2021

Seroprevalence of SARS-CoV-2 antibodies in the poorest region of Brazil: results from a population-based study.

Adriano Antunes de Souza Araújo, Lucindo José Quintans-Júnior, Luana Heimfarth, Dulce Marta Schimieguel, Cristiane Bani Corrêa, Tatiana Rodrigues de Moura, Rafael Ciro Marques Cavalcante, Rangel Rodrigues Bomfim, Renata Grespan, Lorranny Santana Rodrigues and 9 more

Abstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Adriano Antunes de Souza AraújoDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Lucindo José Quintans-JúniorHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.ORCID 0000-0001-5155-938X
Luana HeimfarthHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Dulce Marta SchimieguelDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Cristiane Bani CorrêaHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Tatiana Rodrigues de MouraHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Rafael Ciro Marques CavalcanteDepartment of Pharmacy, Federal University of Sergipe, Lagarto, Sergipe, Brazil.
Rangel Rodrigues BomfimDepartment of Pharmacy, Federal University of Sergipe, Lagarto, Sergipe, Brazil.
Renata GrespanDepartment of Physiology, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Lorranny Santana RodriguesHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Danillo Menezes Dos SantosHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Ayane de Sá ResendeHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Nathanielly de Lima SilvaGraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Anna Clara Ramos da Silva SantosGraduate Program in Pharmaceutical Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Jéssica Maria Dantas AraújoGraduate Program in Physiological Sciences, Federal University of Sergipe, São Cristóvão, Sergipe, Brazil.
Mércia Feitosa de SouzaGovernment of Sergipe State, State Health Secretariat, Aracaju, Sergipe, Brazil.
Marco Aurélio de Oliveira GóesGovernment of Sergipe State, State Health Secretariat, Aracaju, Sergipe, Brazil.ORCID 0000-0003-0953-9320
Victor Santana SantosHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Paulo Ricardo Martins-FilhoHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.ORCID 0000-0001-8779-0727

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Population-based seroprevalence studies on coronavirus disease 2019 (COVID-19) in low- and middle-income countries are lacking. We investigated the seroprevalence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibodies in Sergipe state, Northeast Brazil, using rapid IgM-IgG antibody test and fluorescence immunoassay. The seroprevalence was 9.3% (95% CI 8.5-10.1), 10.2% (95% CI 9.2-11.3) for women and 7.9% (IC 95% 6.8-9.1) for men (P = 0.004). We found a decline in the prevalence of SARS-CoV-2 antibodies according to age, but the differences were not statistically significant: 0-19 years (9.9%; 95% CI 7.8-12.5), 20-59 years (9.3%; 95% CI 8.4-10.3) and ≥60 years (9.0%; 95% CI 7.5-10.8) (P = 0.517). The metropolitan area had a higher seroprevalence (11.7%, 95% CI 10.3-13.2) than outside municipalities (8.0%, 95% CI 7.2-8.9) (P < 0.001). These findings highlight the importance of serosurveillance to estimate the real impact of the COVID-19 outbreak and thereby provide data to better understand the spread of the virus, as well as providing information to guide stay-at-home measures and other policies. In addition, these results may be useful as basic data to follow the progress of COVID-19 outbreak as social restriction initiatives start to be relaxed in Brazil.

Indexed as

AdolescentAdultAgedAged, 80 and overAntibodies, ViralBrazilChildChild, PreschoolCOVID-19Cross-Sectional StudiesFemaleHumansInfantInfant, NewbornMaleMiddle AgedAntibodies, ViralCOVID-19serioepidemiological studiessevere acute respiratory syndrome coronavirus 2

Identifiers

PMID34001292
PMCPMC8160491

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.