Evidence map›Paper›PMID 34001040›Full record

ArticleBMC cancer2021

Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type.

Rui Chen, Liguang Wang, Qi Zhao, Zhen Li, Man Chen, Guodong Lian, Junyong Zhang

Abstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui ChenDepartment of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, 324 Jingwu Road, Jinan, 250021, Shandong, People's Republic of China.
Liguang WangDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Qi ZhaoDepartment of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, 324 Jingwu Road, Jinan, 250021, Shandong, People's Republic of China.
Zhen LiDepartment of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, 324 Jingwu Road, Jinan, 250021, Shandong, People's Republic of China.
Man ChenDepartment of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Guodong LianDepartment of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Junyong ZhangDepartment of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, 324 Jingwu Road, Jinan, 250021, Shandong, People's Republic of China. 13583173280@163.com.ORCID http://orcid.org/0000-0002-0222-8362

Funding

National Natural Science Foundation of China 81902349Natural Science Foundation of Shandong Province ZR2017MH035Natural Science Foundation of Shandong Province ZR2019QH014
6 · The paper itself

Abstract

backgroundThe platelet-to-lymphocyte ratio (PLR) and C-reactive protein (CRP) level are markers that have been reported to predict the histological type of various tumors, and here, we evaluated their utility in predicting colorectal polyp histological types.

methodsWe retrospectively reviewed 172 patients with colorectal polyps who underwent endoscopic polypectomy. The associations between histological type and clinicopathologic parameters were assessed by multivariate analysis.

resultsThe optimal PLR and CRP cut-off values were 113.32 and 0.39, respectively. The PLR (P = 0.002) and CRP (P = 0.009) values were associated with the histological type according to the univariate analysis, whereas low PLR (P ≤ 0.001) and CRP (P = 0.017) values were independent risk factors in the multivariate analysis together with maximum tumor diameter (P ≤ 0.001) and tumor number (P = 0.0014).

conclusionsPreoperative PLR and CRP are correlated with the colorectal polyp histological type.

Indexed as

AdultAgedBiomarkers, TumorBlood PlateletsColonColonic PolypsColonoscopyColorectal NeoplasmsC-Reactive ProteinFemaleHumansIntestinal MucosaLymphocyte CountLymphocytesMaleMiddle AgedBiomarkers, TumorC-Reactive ProteinColorectal polypsC-reactive protein (CRP)Histological typePlatelet-to-lymphocyte ratio (PLR)

Identifiers

PMID34001040
PMCPMC8127289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.