Evidence map›Paper›PMID 34001024›Full record

Trial reportBMC geriatrics2021

Ambient bright light treatment improved proxy-rated sleep but not sleep measured by actigraphy in nursing home patients with dementia: a placebo-controlled randomised trial.

Gunnhild J Hjetland, Eirin Kolberg, Ståle Pallesen, Eirunn Thun, Inger Hilde Nordhus, Bjørn Bjorvatn, Elisabeth Flo-Groeneboom

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03357328 (Therapy Light Rooms for Nursing Home Patients With Dementia - Designing Diurnal Conditions for Improved Sleep, Mood and Behavioural Problems), which is not on this map. Cited by 17 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 5 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03357328 nacompletednot on this map

Therapy Light Rooms for Nursing Home Patients With Dementia - Designing Diurnal Conditions for Improved Sleep, Mood and Behavioural Problems (DEM.LIGHT)

TypeinterventionalSponsorUniversity of BergenRan2017 to 2018Enrolled70ConditionsSleep Fragmentation, Behavioural and Psychiatric Symptoms of Dementia, DementiaArmsTherapy light room, Standard light
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Gunnhild J HjetlandDepartment of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway. Gunnhildjohnsen.Hjetland@fhi.no.ORCID 0000-0003-3450-3186
Eirin KolbergDepartment of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.
Ståle PallesenNorwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Bergen, Norway.
Eirunn ThunDepartment of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.
Inger Hilde NordhusDepartment of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.
Bjørn BjorvatnNorwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Bergen, Norway.
Elisabeth Flo-GroeneboomDepartment of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Norway.
University of Bergen · NOHaukeland University Hospital · NONorwegian Institute of Public Health · NOUniversity of Oslo · NO

Funding

Norges Forskningsråd 259987/H40
6 · The paper itself

Abstract

backgroundUp to 70% of nursing home patients with dementia suffer from sleep problems. Light is the main zeitgeber to the circadian system and thus has a fundamental impact on sleep-wake behaviour. Low indoor light levels in nursing homes have been reported, and in combination with age-related reductions in light sensitivity, insufficient light exposure is likely to contribute to sleep problems in this population. Increasing daytime light exposure using bright light treatment (BLT) may represent a feasible non-pharmacological treatment for sleep problems in nursing home patients with dementia.

methodsThe present study reports on sleep outcomes, which are the primary outcomes of the DEM.LIGHT trial (Therapy Light Rooms for Nursing Home Patients with Dementia- Designing Diurnal Conditions for Improved Sleep, Mood and Behavioural Problems), a 24-week cluster-randomised placebo-controlled trial including 8 nursing home units and 69 resident patients. The intervention comprised ambient light of 1000 lx and 6000 K from 10:00 to 15:00, with gradually increasing and decreasing light levels prior to and following this interval, using ceiling mounted light-fixtures and light emitting diode technology. The placebo condition had continuous standard light levels (150-300 lx, ~ 3000 K). Sleep was assessed at baseline and follow-up at week 8, 16, and 24, using the proxy-rated Sleep Disorder Inventory (SDI) and actigraphy (Actiwatch II, Philips Respironics). Mixed linear models were used to evaluate intervention effects, adjusting for relevant covariates such as age, gender, number of drugs, severity of dementia, eye disease, and estimated light exposure.

resultsSleep as measured by the SDI was significantly improved in the intervention group compared to the control group from baseline to week 16 (B = - 0.06, 95% CI -0.11 - -0.01, p < .05) and from baseline to week 24 (B = - 0.05, 95% CI -0.10 - -0.01, p < .05). There was no effect according to the SDI at week 8 and no significant effects in terms of actigraphically measured sleep.

conclusionsProxy-rated sleep improved among nursing home patients with dementia following 16 and 24 weeks of BLT. These improvements were not corroborated by actigraphy recordings.

trial registrationClinicalTrials.gov Identifier: NCT03357328 . Registered 29 November 2017 - Retrospectively registered.

Indexed as

DementiaSleep Wake DisordersActigraphyHumansNursing HomesSleepActigraphyDementiaNursing homeSleepSleep disorder inventory

Identifiers

PMID34001024
PMCPMC8127192
OpenAlexW3161255990

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.