Evidence map›Paper›PMID 34000419›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2021

Clinical presentation, outcomes and factors associated with mortality: A prospective study from three COVID-19 referral care centres in West Africa.

Marie Jaspard, Mamadou Saliou Sow, Sylvain Juchet, Eric Dienderé, Beatrice Serra, Richard Kojan, Billy Sivahera, Caroline Martin, Moumouni Kinda, Hans-Joerg Lang and 19 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  13. Long COVID symptoms in a population-based sample of persons discharged home from hospital.Canadian journal of public health = Revue canadienne de sante publique · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Marie JaspardThe Alliance for International Medical Action (ALIMA), Dakar, Senegal; Inserm 1219, Univ. Bordeaux, IRD, Bordeaux, France.
Mamadou Saliou SowService des Maladies Infectieuses, Hôpital National Donka, Conakry, Guinea.
Sylvain JuchetThe Alliance for International Medical Action (ALIMA), Dakar, Senegal; Inserm 1219, Univ. Bordeaux, IRD, Bordeaux, France.
Eric DienderéService de Médecine interne - Maladies Infectieuses, CHU de Bogodogo, Ouagadougou, Burkina Faso.
Beatrice SerraThe Alliance for International Medical Action (ALIMA), Dakar, Senegal; Inserm 1219, Univ. Bordeaux, IRD, Bordeaux, France.
Richard KojanThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Billy SivaheraThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Caroline MartinThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Moumouni KindaThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Hans-Joerg LangThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Fodé Bangaly SakoService des Maladies Infectieuses, Hôpital National Donka, Conakry, Guinea.
Fodé Amara TraoréService des Maladies Infectieuses, Hôpital National Donka, Conakry, Guinea.
Eudoxie KoumbemThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Halidou TintoClinical Research Unit of Nanoro, National Center for Scientific and Technological Research, Ouagadougou, Burkina Faso.
Adama SanouDirection des services médicaux et médicotechniques du Centre Hospitalier Universitaire de Tengandogo, Ouagadougou, Burkina Faso.
Apoline SondoService des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
Flavien KaboréService d'anesthésie réanimation, Centre Hospitalier Universitaire de Tengandogo, Ouagadougou, Burkina Faso.
Joseph DonamouService d'anesthésie et de réanimation, Hôpital National Donka, Conakry, Guinea.
Jean-Paul-Yassa GuilavoguiThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Fanny VelardoInserm 1219, Univ. Bordeaux, IRD, Bordeaux, France.
Brice BicabaCentre des Opérations et Réponses aux Urgences Sanitaires du Burkina Faso, Ouagadougou, Burkina Faso.
Olivier MarcyInserm 1219, Univ. Bordeaux, IRD, Bordeaux, France.
Augustin AugierThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Sani SayadiThe Alliance for International Medical Action (ALIMA), Dakar, Senegal.
Armel PodaInstitut National des Sciences de la Santé (INSSA), Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Sakoba KeitaAgence Nationale de Sécurité Sanitaire (ANSS), Conakry, Guinea.
Xavier AnglaretThe Alliance for International Medical Action (ALIMA), Dakar, Senegal; Inserm 1219, Univ. Bordeaux, IRD, Bordeaux, France.
Denis MalvyInserm 1219, Univ. Bordeaux, IRD, Bordeaux, France; Department of Infectious Diseases and Tropical Medicine, CHU de Bordeaux, Hôpital Pellegrin, Bordeaux, France. Electronic address: denis.malvy@chu-bordeaux.fr.
COVISTA study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe overall death toll from COVID-19 in Africa is reported to be low but there is little individual-level evidence on the severity of the disease. This study examined the clinical spectrum and outcome of patients monitored in COVID-19 care centres (CCCs) in two West-African countries.

methodsBurkina Faso and Guinea set up referral CCCs to hospitalise all symptomatic SARS-CoV-2 carriers, regardless of the severity of their symptoms. Data collected from hospitalised patients by November 2020 are presented.

resultA total of 1,805 patients (64% men, median age 41 years) were admitted with COVID-19. Symptoms lasted for a median of 7 days (IQR 4-11). During hospitalisation, 443 (25%) had a SpO2 < 94% at least once, 237 (13%) received oxygen and 266 (15%) took corticosteroids. Mortality was 5% overall, and 1%, 5% and 14% in patients aged <40, 40-59 and ≥60 years, respectively. In multivariable analysis, the risk of death was higher in men (aOR 2.0, 95% CI 1.1; 3.6), people aged ≥60 years (aOR 2.9, 95% CI 1.7; 4.8) and those with chronic hypertension (aOR 2.1, 95% CI 1.2; 3.4).

conclusionCOVID-19 is as severe in Africa as elsewhere, and there must be more vigilance for common risk factors such as older age and hypertension.

Indexed as

COVID-19AdultAgedBurkina FasoFemaleHospitalizationHumansMaleProspective StudiesReferral and ConsultationSARS-CoV-2ComorbiditiesCOVID-19MortalitySARS-Cov-2Sub-Saharan Africa

Identifiers

PMID34000419
PMCPMC8120805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.