Evidence map›Paper›PMID 34000299›Full record

ArticleThe Journal of biological chemistry

Calcium as a reliable marker for the quantitative assessment of endoplasmic reticulum stress in live cells.

Paul F Lebeau, Khrystyna Platko, Jae Hyun Byun, Richard C Austin

Open access · goldAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Resting CaCellular and molecular life sciences : CMLS · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Calcium imaging: a technique to monitor calcium dynamics in biological systems.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Review
  12. Impaired intracellular CaScience signaling · 2023
    Article
  13. Article
  14. ER CaCell & bioscience · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paul F LebeauDepartment of Medicine, Division of Nephrology, McMaster University, The Research Institute of St Joe's Hamilton and Hamilton Centre for Kidney Research, Hamilton, Ontario, Canada.
Khrystyna PlatkoDepartment of Medicine, Division of Nephrology, McMaster University, The Research Institute of St Joe's Hamilton and Hamilton Centre for Kidney Research, Hamilton, Ontario, Canada.
Jae Hyun ByunDepartment of Medicine, Division of Nephrology, McMaster University, The Research Institute of St Joe's Hamilton and Hamilton Centre for Kidney Research, Hamilton, Ontario, Canada.
Richard C AustinDepartment of Medicine, Division of Nephrology, McMaster University, The Research Institute of St Joe's Hamilton and Hamilton Centre for Kidney Research, Hamilton, Ontario, Canada. Electronic address: austinr@taari.ca.
St. Joseph’s Healthcare Hamilton · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium (Ca

Indexed as

Endoplasmic Reticulum StressCalciumCell LineEndoplasmic ReticulumHEK293 CellsHep G2 CellsHumansMicroscopy, FluorescenceUnfolded Protein ResponseCalciumcalciumendoplasmic reticulum stress (ER stress)Mag-Fluo-4unfolded protein response (UPR)

Identifiers

PMID34000299
PMCPMC8191341
OpenAlexW3161691797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.