SynthesisInteractive cardiovascular and thoracic surgery2021
A pooled analysis of pacemaker implantation after Perceval sutureless aortic valve replacement.
Synthesis in Interactive cardiovascular and thoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Perceval valve intermediate outcomes: a systematic review and meta-analysis at 5-year follow-up.Journal of cardiothoracic surgery · 2023Pooled it
- Mechanisms of Trifecta Valve Failure and Contemporary Approaches to Reintervention: Perceval vs Valve-in-Valve Transcatheter Aortic Valve Implantation.Interdisciplinary cardiovascular and thoracic surgery · 2026Review
- Comparison of Surgical Treatment Outcomes in Patients with Symptomatic Severe Aortic Valve Stenosis Using the Perceval Sutureless Bioprosthesis Versus a Conventional Biological Valve.Journal of cardiovascular development and disease · 2025Article
- Article
- Comparative Analysis of Perceval and Conventional Bovine Bioprosthetic Valves in Aortic Valve Replacement: Hemodynamics, Reverse Remodeling, and Long-Term Outcomes.Journal of clinical medicine · 2025Article
- Repositioning of the membranous septum to minimize pacemaker implantation after sutureless surgical aortic valve replacement.JTCVS techniques · 2023Article
- Rapid-Deployment Aortic Valve Replacement: Patient Selection and Special Considerations.Vascular health and risk management · 2023Review
- Sutureless aortic valve replacement in patients with active infective endocarditis: is it contraindicated or recommended?Journal of thoracic disease · 2022Article
- Avoiding oversizing in sutureless valves leads to lower transvalvular gradients and less permanent pacemaker implants postoperatively.Interactive cardiovascular and thoracic surgery · 2022Article
- Commentary: Similar rhythm disturbance profiles of rapid-deployment aortic valve bioprostheses.JTCVS techniques · 2021Article
- The Perceval Sutureless Bioprosthetic Aortic Valve: Evolution of Surgical Valve Technology.Innovations (Philadelphia, Pa.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe performed a literature meta-analysis to estimate the rate of pacemaker implantation after Perceval sutureless aortic valve replacement.
methodsPertinent articles were identified from the PubMed, Google Scholar, Ovid MEDLINE and Ovid EMBASE databases. Eligible studies reported the de novo incidence of postoperative pacemaker implantation after Perceval valve surgery. Among 394 articles retrieved, 26 studies including 9492 patients met the inclusion criteria.
resultsThe pooled event rate for postoperative pacemaker implantation was 7% [95% confidence interval (CI) 6-9%]; however, significant heterogeneity was observed across studies. In a sub-analysis, there was no difference between the rates of pacemaker implantation calculated from multicentre and registry studies (8 studies, 6845 patients; 7%, 95% CI 5-10%) and single-centre studies (18 studies, 2647 patients; 7%, 95% CI 5-9%; P = 0.75). Implantation rates were similar in high-volume studies (16 studies, 9121 patients; 7%, 95% CI 5-8%) than in low-volume studies (10 studies, 371 patients; pooled rate: 7%, 95% CI 4-14%; P = 0.5). Postoperative pacemaker implantation rates tended to decrease over time.
conclusionsWith a pooled event rate of 7%, postoperative pacemaker implantation remains an important limitation of Perceval sutureless valve surgery, although we observed a degree of variability across included studies. The resultant findings provide a useful estimate for physicians and patients and can serve as a benchmark for future comparative studies. PROSPERO REGISTRATION NUMBER: CRD42020188397.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.