Evidence map›Paper›PMID 33999961›Full record

ArticlePloS one2021

Dimensions of HIV-related stigma in rural communities in Kenya and Uganda at the start of a large HIV 'test and treat' trial.

Cecilia Akatukwasa, Monica Getahun, Alison M El Ayadi, Judith Namanya, Irene Maeri, Harriet Itiakorit, Lawrence Owino, Naomi Sanyu, Jane Kabami, Emmanuel Ssemmondo and 11 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 3 countries.

Cecilia AkatukwasaInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0002-1157-9797
Monica GetahunDepartment of Obstetrics, Bixby Center for Global Reproductive Health, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, United States of America.
Alison M El AyadiDepartment of Obstetrics, Bixby Center for Global Reproductive Health, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, United States of America.
Judith NamanyaInfectious Diseases Research Collaboration, Kampala, Uganda.
Irene MaeriCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Harriet ItiakoritInfectious Diseases Research Collaboration, Kampala, Uganda.
Lawrence OwinoCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Naomi SanyuInfectious Diseases Research Collaboration, Kampala, Uganda.
Jane KabamiInfectious Diseases Research Collaboration, Kampala, Uganda.
Emmanuel SsemmondoInfectious Diseases Research Collaboration, Kampala, Uganda.
Norton SangCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Dalsone KwarisiimaInfectious Diseases Research Collaboration, Kampala, Uganda.
Maya L PetersenDivisions of Biostatistics and Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, CA, United States of America.
Edwin D CharleboisCenter for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA, United States of America.
Gabriel ChamieDivision of HIV, Infectious Disease and Global Medicine, Department of Medicine, University of California, San Francisco, CA, United States of America.
Tamara D ClarkDivision of HIV, Infectious Disease and Global Medicine, Department of Medicine, University of California, San Francisco, CA, United States of America.
Craig R CohenDepartment of Obstetrics, Bixby Center for Global Reproductive Health, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, United States of America.
Moses R KamyaInfectious Diseases Research Collaboration, Kampala, Uganda.
Elizabeth A BukusiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Diane V HavlirDivision of HIV, Infectious Disease and Global Medicine, Department of Medicine, University of California, San Francisco, CA, United States of America.
Carol S CamlinDepartment of Obstetrics, Bixby Center for Global Reproductive Health, Gynecology & Reproductive Sciences, University of California, San Francisco, CA, United States of America.
Infectious Diseases Research Collaboration · UGUniversity of California, San Francisco · USKenya Medical Research Institute · KEIbis Reproductive Health · USUniversity of California, Berkeley · US

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Reducing Failure-to-Initiate ART: Streamlined ART Start Strategy (START)U01AI099959 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAVLIR, DIANE V · 2012 to 2016
$39.7M
NIAID NIH HHS U01 AI099959NIAID NIH HHS UM1 AI068636NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

HIV-related stigma is a frequently cited barrier to HIV testing and care engagement. A nuanced understanding of HIV-related stigma is critical for developing stigma-reduction interventions to optimize HIV-related outcomes. This qualitative study documented HIV-related stigma across eight communities in east Africa during the baseline year of a large HIV test-and-treat trial (SEARCH, NCT: 01864603), prior to implementation of widespread community HIV testing campaigns and efforts to link individuals with HIV to care and treatment. Findings revealed experiences of enacted, internalized and anticipated stigma that were highly gendered, and more pronounced in communities with lower HIV prevalence; women, overwhelmingly, both held and were targets of stigmatizing attitudes about HIV. Past experiences with enacted stigma included acts of segregation, verbal discrimination, physical violence, humiliation and rejection. Narratives among women, in particular, revealed acute internalized stigma including feelings of worthlessness, shame, embarrassment, and these resulted in anxiety and depression, including suicidality among a small number of women. Anticipated stigma included fears of marital dissolution, verbal and physical abuse, gossip and public ridicule. Anticipated stigma was especially salient for women who held internalized stigma and who had experienced enacted stigma from their partners. Anticipated stigma led to care avoidance, care-seeking at remote facilities, and hiding of HIV medications. Interventions aimed at reducing individual and community-level forms of stigma may be needed to improve the lives of PLHIV and fully realize the promise of test-and-treat strategies.

Indexed as

StereotypingAdolescentAdultAgedAnti-Retroviral AgentsFemaleHIV InfectionsHumansInterviews as TopicKenyaMaleMiddle AgedPatient Acceptance of Health CareRural PopulationSurveys and QuestionnairesUgandaAnti-Retroviral Agents

Identifiers

PMID33999961
PMCPMC8128261
OpenAlexW3161232216

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.