Evidence map›Paper›PMID 33999831›Full record

Observational studyJMIR public health and surveillance2021

Correlation of Population SARS-CoV-2 Cycle Threshold Values to Local Disease Dynamics: Exploratory Observational Study.

Chak Foon Tso, Anurag Garikipati, Abigail Green-Saxena, Qingqing Mao, Ritankar Das

Abstract readObservational Study
In one paragraph

Observational study in JMIR public health and surveillance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. SARS-CoV-2 cycle threshold (Ct) values predict future COVID-19 cases.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chak Foon TsoDascena, Inc, Houston, TX, United States.ORCID 0000-0002-6339-4276
Anurag GarikipatiDascena, Inc, Houston, TX, United States.ORCID 0000-0002-2230-2187
Abigail Green-SaxenaDascena, Inc, Houston, TX, United States.ORCID 0000-0002-8502-6589
Qingqing MaoDascena, Inc, Houston, TX, United States.ORCID 0000-0001-6001-6723
Ritankar DasDascena, Inc, Houston, TX, United States.ORCID 0000-0002-1326-844X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the limitations in the use of cycle threshold (CT) values for individual patient care, population distributions of CT values may be useful indicators of local outbreaks.

objectiveWe aimed to conduct an exploratory analysis of potential correlations between the population distribution of cycle threshold (CT) values and COVID-19 dynamics, which were operationalized as percent positivity, transmission rate (R

methodsIn total, 148,410 specimens collected between September 15, 2020, and January 11, 2021, from the greater El Paso area were processed in the Dascena COVID-19 Laboratory. The daily median CT value, daily R

resultsDaily median CT values negatively correlated with the daily R

conclusionsThis study adds to the literature by analyzing samples collected from an entire geographical area and contextualizing the results with other research investigating population CT values.

Indexed as

AdultCOVID-19COVID-19 Nucleic Acid TestingFemaleHospitalizationHumansMaleMiddle AgedPandemicsSARS-CoV-2TexasTime FactorscorrelationCOVID-19cycle thresholddisease dynamicdistributionepidemiologyexploratorypopulationreverse transcription polymerase chain reactionRttestingthresholdtransmission

Identifiers

PMID33999831
PMCPMC8176948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.