Evidence map›Paper›PMID 33999800›Full record

ReviewCanadian Urological Association journal = Journal de l'Association des urologues du Canada2021

Enhanced recovery after cystectomy in patients with preoperative narcotic use.

Saum Ghodoussipour, Alireza Ghoreifi, Behdod Katebian, Brian H Cameron, Anirban P Mitra, Jie Cai, Gus Miranda, Anne K Schuckman, Siamak Daneshmand, Hooman Djaladat

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Saum GhodoussipourInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Alireza GhoreifiInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Behdod KatebianInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Brian H CameronInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Anirban P MitraInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Jie CaiInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Gus MirandaInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Anne K SchuckmanInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Siamak DaneshmandInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
Hooman DjaladatInstitute of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, United States.
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to evaluate the outcomes of radical cystectomy with an enhanced recovery after surgery (ERAS) protocol in patients with a history of chronic preoperative narcotic use compared to narcotic-naive patients.

methodsWe identified 553 patients who underwent open radical cystectomy with ERAS. Preoperative narcotic use was identified in 34 patients who were then matched to 68 narcotic-naive patients. Postoperative outcomes, opioid use, and visual analog scale (VAS) pain scores were analyzed and compared. All routes of opioid use were recorded and converted to a morphine equivalent dose (MED).

resultsPatients with preoperative narcotic use reported higher median VAS pain scores per day (postoperative day [POD1]: 5.2 vs. 3.9, p=0.003; POD2: 5.1 vs. 3.6, p<0.001; POD3: 4.6 vs. 3.8, p=0.004) and used significantly more opioids (median MED) per day (POD1: 13.2 vs. 10.0, p=0.02; POD2: 11.3 vs. 6.4, p=0.003; POD3: 10.2 vs. 5.0, p=0.005) following surgery. Preoperative narcotic users were noted to have a significantly higher incidence of 90-day re-admissions (41.2% vs. 20.6%, p=0.03). There was no difference in median hospital stay (4 vs. 4 days, p=0.6), 30-or 90-day complications (64.7% vs. 60.3%, p=0.8 and 82.4% vs. 75.0%, p=0.4, respectively) or gastrointestinal complications (29.4% vs. 26.5%, p=0.8), including postoperative ileus (11.8% vs. 20.6%, p=0.2).

conclusionsPatients with preoperative narcotic exposure report higher pain scores and require more opioid use following radical cystectomy with ERAS and are more likely to be re-admitted within 90 days. However, there was no observed difference in hospital stay or complications.

Identifiers

PMID33999800
PMCPMC8525533
OpenAlexW3162119402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.