Evidence map›Paper›PMID 33999662›Full record

ArticleCirculation2021

Optimizing Adeno-Associated Virus Serotype 9 for Studies of Cardiac Chamber-Specific Gene Regulation.

Alina S Bilal, Erik A Blackwood, Donna J Thuerauf, Christopher C Glembotski

Abstract readLetter
In one paragraph

Article in Circulation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Gene Therapy for Inherited Cardiac Arrhythmias.Journal of cardiovascular translational research · 2025
    Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alina S BilalTranslational Cardiovascular Research Center and Department of Internal Medicine, University of Arizona College of Medicine-Phoenix (A.S.B., E.A.B., C.C.G.).
Erik A BlackwoodTranslational Cardiovascular Research Center and Department of Internal Medicine, University of Arizona College of Medicine-Phoenix (A.S.B., E.A.B., C.C.G.).
Donna J ThueraufDepartment of Cellular and Molecular Biology, San Diego State University, CA (D.J.T.).
Christopher C GlembotskiTranslational Cardiovascular Research Center and Department of Internal Medicine, University of Arizona College of Medicine-Phoenix (A.S.B., E.A.B., C.C.G.).

Funding

Non-canonical ERAD as a Regulator of Cardiac HypertrophyR01HL157027 · NHLBI · UNIVERSITY OF ARIZONA · PI GLEMBOTSKI, CHRIS · 2022 to 2025
$2.6M
The ER Stress-Induced Selenoprotein, SelenoS, Regulates Proteostasis and Cardiac HypertrophyR01HL149931 · NHLBI · UNIVERSITY OF ARIZONA · PI GLEMBOTSKI, CHRIS · 2020 to 2023
$1.7M
Harnessing the Adaptive ER Stress Response in Myocardial IschemiaR01HL135893 · NHLBI · UNIVERSITY OF ARIZONA · PI GLEMBOTSKI, CHRIS · 2017 to 2020
$1.5M
ATF6 is Required for ANP Secretion from the HeartR01HL141463 · NHLBI · UNIVERSITY OF ARIZONA · PI GLEMBOTSKI, CHRIS · 2019 to 2022
$1.5M
The Adaptive Cardiac Sensor, ATF6, Regulates ANP Secretion and Decreases Hypertensive StressF31HL140850 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI BLACKWOOD, ERIK · 2018 to 2020
$69k
NHLBI NIH HHS F31 HL140850NHLBI NIH HHS R01 HL135893NHLBI NIH HHS R01 HL141463NHLBI NIH HHS R01 HL149931NHLBI NIH HHS R01 HL157027
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenoviridaeAnimalsGene Regulatory NetworksHeartHumansMiceSerotypingadeno-associated viruscardiacheart atriaheart ventriclemyocytestissue specificity

Identifiers

PMID33999662
PMCPMC8529561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.