Evidence map›Paper›PMID 33999430›Full record

ArticleAlcoholism, clinical and experimental research2021

Partner influence as a factor in maternal alcohol consumption and depressive symptoms, and maternal effects on infant neurodevelopmental outcomes.

Carson Kautz-Turnbull, Christie L M Petrenko, Elizabeth D Handley, Claire D Coles, Julie A Kable, Wladimir Wertelecki, Lyubov Yevtushok, Natalya Zymak-Zakutnya, Christina D Chambers, Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD)

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Carson Kautz-TurnbullMt. Hope Family Center, University of Rochester, Rochester, NY, USA.ORCID 0000-0002-0419-0177
Christie L M PetrenkoMt. Hope Family Center, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-2091-3686
Elizabeth D HandleyMt. Hope Family Center, University of Rochester, Rochester, NY, USA.
Claire D ColesDepartments of Psychiatry and Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-3399-6644
Julie A KableDepartments of Psychiatry and Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0001-5008-0887
Wladimir WerteleckiDepartment of Medical Genetics, University of South Alabama, Mobile, AL, USA.
Lyubov YevtushokOMNI-Net Centers, Rivne and Kherson Oblasts, Ukraine.
Natalya Zymak-ZakutnyaOMNI-Net for Children International Charitable Fund, Khmelnytsky Perinatal Center, Khmelnytsky, Khmelnytsky Province, Ukraine.
Christina D ChambersDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-4675-7722
Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD)
University of Rochester · USEmory University · USKhmelnytskyi National University · UARivne State University of Humanities · UAUniversity of California San Diego · US

Funding

Whole Body Effects of PAE Across the Life Span: Early Markers of & Clinical Interventions for Children and Adolescents in UkraineU01AA014835 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHRISTINA CHAMBERS · 2003 to 2026
$12.1M
International Collaboration to Develop Scalable Methods for Early Detection of Neurodevelopmental Disorder Due to Prenatal Alcohol ExposureR01AA026579 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHAMBERS, CHRISTINA, KABLE, JULIE A · 2018 to 2022
$1.7M
NIAAA NIH HHS R01 AA026579NIAAA NIH HHS U01 AA014835
6 · The paper itself

Abstract

backgroundFew studies have investigated the partner's influence on risk factors such as alcohol consumption and depression during pregnancy. Partner substance use and lower relationship satisfaction predict higher maternal alcohol use and depressive symptoms. Because prenatal alcohol use and maternal depression affect infant outcomes, it is imperative to examine how the partner affects these maternal risk factors. The current study examined the effect of a latent construct of partner influence on maternal alcohol use and depressive symptoms, and the effects on infant development of these maternal factors.

methodsParticipants were 246 pregnant women from 2 sites in Western Ukraine from whom longitudinal data were collected as part of a multisite study. In the first trimester, mothers reported on relationship satisfaction, partner substance use, and socioeconomic status (SES). In the third trimester, they reported on alcohol use and depressive symptoms. Infants were assessed using the Bayley Scale of Infant Development (average age = 6.93 months). A latent construct titled partner influence was formed using partner substance use and measures of relationship satisfaction, including the frequency of quarreling, happiness in the relationship, and the ease of talking with the partner. Using structural equation modeling, a model was specified in which partner influence and SES predicted maternal alcohol use and depressive symptoms, which in turn predicted infant neurodevelopmental outcomes.

resultsHigher partner influence significantly predicted lower prenatal alcohol use and lower depressive symptoms, controlling for the effect of SES. Higher maternal prenatal alcohol use significantly predicted lower infant mental and psychomotor development. Maternal depressive symptoms did not predict infant development over and above the effect of alcohol use.

conclusionsPartner influence is an important contributor to prenatal alcohol use and maternal depressive symptoms, over and above the effect of SES. The significant paths from prenatal alcohol exposure to infant neurodevelopmental outcomes underscore the importance of partner influence during pregnancy.

Indexed as

Latent Class AnalysisAdolescentAdultAlcohol DrinkingChild DevelopmentDepressionFemaleHumansInfant, NewbornMarriageMaternal ExposureNervous SystemPregnancyPregnancy ComplicationsPrenatal Exposure Delayed EffectsProspective Studiesinfantpartner influencepregnancyprenatal alcoholrelationship

Identifiers

PMID33999430
PMCPMC8254755
OpenAlexW3162539695

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.