Evidence map›Paper›PMID 33999108›Full record

SynthesisAdvances in nutrition (Bethesda, Md.)2021

Healthy Food Prescription Programs and their Impact on Dietary Behavior and Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis.

Saiuj Bhat, Daisy H Coyle, Kathy Trieu, Bruce Neal, Dariush Mozaffarian, Matti Marklund, Jason H Y Wu

3 registry-linked trialsOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Advances in nutrition (Bethesda, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 90 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 4 pooled it
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05939349 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Prescription for Health Equity: A Healthcare Provider-based Produce Prescription Program for People With Prediabetes and Type 2 Diabetes

TypeinterventionalSponsorGriffin HospitalRan2023 to 2025Enrolled134ConditionsPre Diabetes, Diabetes Mellitus, Type 2ArmsProduce Prescription Group
NCT05978843 nacompletednot on this mapstarted 2024, after this paper: background citation

Comparison of Produce Prescription Benefit Dosage on Redemption

TypeinterventionalSponsorUniversity of California, San FranciscoRan2024 to 2024Enrolled242ConditionsFood InsecurityArmsMonetary benefit to purchase fruits and vegetables
NCT06614920 narecruitingnot on this mapstarted 2025, after this paper: background citation

Addressing Food-Insecurity: Plant-Based Food Prescription Program to Improve Health Food Access

TypeinterventionalSponsorUniversity of MiamiRan2025 to 2028Enrolled100ConditionsHealth Literacy, Nutrition, Healthy, Nutrition Poor, Food InsecurityArmsPlant-Based Food Provision (with or without food prescription), Plant-Based Nutrition Education
3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 4 syntheses or guidelines pooled it, 144 citations in OpenAlex.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Saiuj BhatSchool of Medicine, The University of Western Australia, Crawley, Australia.ORCID 0000-0002-8746-4259
Daisy H CoyleThe George Institute for Global Health, University of New South Wales, Sydney, Australia.ORCID 0000-0001-8904-0671
Kathy TrieuThe George Institute for Global Health, University of New South Wales, Sydney, Australia.
Bruce NealThe George Institute for Global Health, University of New South Wales, Sydney, Australia.
Dariush MozaffarianFriedman School of Nutrition Science and Policy, Tufts University, Boston, MA, USA.ORCID 0000-0001-7958-9492
Matti MarklundThe George Institute for Global Health, University of New South Wales, Sydney, Australia.
Jason H Y WuThe George Institute for Global Health, University of New South Wales, Sydney, Australia.
UNSW Sydney · AUJohns Hopkins University · USThe University of Western Australia · AUTufts University · US

Funding

Cost-Effectiveness of Health System and State-Level Strategies to Improve Diet and Reduce Cardiometabolic DiseasesR01HL115189 · NHLBI · TUFTS UNIVERSITY BOSTON · PI DARIUSH MOZAFFARIAN · 2013 to 2026
$8.2M
NHLBI NIH HHS R01 HL115189
6 · The paper itself

Abstract

The enormous burden of diet-related chronic diseases has prompted interest in healthy food prescription programs. Yet, the impact of such programs remains unclear. The aim of this study was to conduct a systematic review of healthy food prescription programs and evaluate their impact on dietary behavior and cardiometabolic parameters by meta-analysis. A systematic search was carried out in Medline, Embase, Scopus, and Cochrane Central Register of Controlled Trials databases since their inception to 3 January, 2020 without language restriction. A systematic search of interventional studies investigating the effect of healthy food prescription on diet quality and/or cardiometabolic risk factors including BMI, systolic (SBP) and diastolic blood pressure (DBP), glycated hemoglobin (HbA1c), or blood lipids was carried out. Thirteen studies were identified for inclusion, most of which were quasi-experimental (pre/post) interventions without a control group (n = 9). Pooled estimates revealed a 22% (95% CI: 12, 32; n = 5 studies, n = 1039 participants; I2 = 97%) increase in fruit and vegetable consumption, corresponding to 0.8 higher daily servings (95% CI: 0.2, 1.4; I2 = 96%). BMI decreased by 0.6 kg/m2 (95% CI: 0.2, 1.1; I2 = 6.4%) and HbA1c by 0.8% (95% CI: 0.1, 1.6; I2 = 92%). No significant change was observed in other cardiometabolic parameters. These findings should be interpreted with caution in light of considerable heterogeneity, methodological limitations of the included studies, and moderate to very low certainty of evidence. Our results support the need for well-designed, large, randomized controlled trials in various settings to further establish the efficacy of healthy food prescription programs on diet quality and cardiometabolic health.

Indexed as

Cardiovascular DiseasesVegetablesDietFruitHumansPrescriptionschronic diseasesculinary medicinedietfood insecurityfood is medicinefood pharmacyfood policyglobal burden of diseasenutritionpublic health

Identifiers

PMID33999108
PMCPMC8483962
OpenAlexW3160912470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.