Evidence map›Paper›PMID 33999021›Full record

ArticleJournal of visualized experiments : JoVE2021

Isolating and Imaging Live, Intact Pacemaker Regions of Mouse Renal Pelvis by Vibratome Sectioning.

Nathan Grainger, Kenton M Sanders, Bernard T Drumm

Open access · greenAbstract readVideo-Audio Media
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of visualized experiments : JoVE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Nathan GraingerDepartment of Physiology & Cell Biology, University of Nevada, Reno School of Medicine; Department of Physiology & Membrane Biology, University of California School of Medicine.
Kenton M SandersDepartment of Physiology & Cell Biology, University of Nevada, Reno School of Medicine.
Bernard T DrummDepartment of Physiology & Cell Biology, University of Nevada, Reno School of Medicine; Department of Life & Health Sciences, Dundalk Institute of Technology; bernard.drumm@dkit.ie.
University of Nevada, Reno · US

Funding

Single Cell Molecular ExpressionP30GM110767 · NIGMS · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2014 to 2018
$5.4M
Pacemaker cells and mechanism in the renal pelvisR01DK124509 · NIDDK · UNIVERSITY OF NEVADA RENO · PI SANDERS, KENTON M · 2020 to 2023
$1.9M
NIDDK NIH HHS R01 DK124509NIGMS NIH HHS P30 GM110767
6 · The paper itself

Abstract

The renal pelvis (RP) is a funnel-shaped, smooth muscle structure that facilitates normal urine transport from the kidney to the ureter by regular, propulsive contractions. Regular RP contractions rely on pacemaker activity, which originates from the most proximal region of the RP at the pelvis-kidney junction (PKJ). Due to the difficulty in accessing and preserving intact preparations of the PKJ, most investigations on RP pacemaking have focused on single-cell electrophysiology and Ca

Indexed as

Histocytological Preparation TechniquesAnimalsKidney PelvisMaleMice, TransgenicMuscle, SmoothPeristalsis

Identifiers

PMID33999021
PMCPMC8609910
OpenAlexW3163387282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.