Evidence map›Paper›PMID 33998882›Full record

Trial reportCannabis and cannabinoid research2022

Effects of Cannabidiol Chewing Gum on Perceived Pain and Well-Being of Irritable Bowel Syndrome Patients: A Placebo-Controlled Crossover Exploratory Intervention Study with Symptom-Driven Dosing.

Anne-Claire B van Orten-Luiten, Nicole M de Roos, Soumia Majait, Ben J M Witteman, Renger F Witkamp

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cannabis and cannabinoid research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Irritable Bowel Syndrome Clinical Care Gaps and the Potential of Future Therapeutics Based on Peripheral Visceral Afferent Modulation.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Medicinal Cannabis and the Intestinal Microbiome.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Cannabinoids and the Gastrointestinal Tract.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Review
  14. Review
  15. Cannabidiol and Intestinal Motility: a Systematic Review.Current developments in nutrition · 2023
    Review
  16. The therapeutic potential of purified cannabidiol.Journal of cannabis research · 2023
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anne-Claire B van Orten-LuitenDivision of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Nicole M de RoosDivision of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Soumia MajaitDivision of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Ben J M WittemanDivision of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Renger F WitkampDivision of Human Nutrition, Wageningen University, Wageningen, The Netherlands.
Wageningen University & Research · NLZiekenhuis Gelderse Vallei · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CannabidiolIrritable Bowel SyndromeAbdominal PainChewing GumCross-Over StudiesFemaleHumansPain PerceptionQuality of LifeCannabidiolChewing Gumcannabidiolchewing gumirritable bowel syndrome

Identifiers

PMID33998882
PMCPMC9418368
OpenAlexW3130351452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.