Evidence map›Paper›PMID 33998690›Full record

SynthesisClinical cardiology2021

The use of minimal fluoroscopy for cardiac electrophysiology procedures: A meta-analysis and review of the literature.

Lorraine Lok Wing Chiang, Christien Li, Kathryn L Hong, Winsy Sin Hui, Sze Yi Beh, Mengqi Gong, Tong Liu, Guangping Li, Yunlong Xia, Jeffery Ho and 7 more

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Clinical cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 6 countries.

Lorraine Lok Wing ChiangLi Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Christien LiDepartment of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Kathryn L HongDivision of Cardiology, University of Toronto, Toronto, Ontario, Canada.
Winsy Sin HuiFaculty of Medicine, Newcastle University, Newcastle, UK.
Sze Yi BehFaculty of Medicine, Newcastle University, Newcastle, UK.
Mengqi GongTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Guangping LiTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China.
Yunlong XiaDepartment of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jeffery HoDepartment of Anaesthesia and Intensive care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Leonardo RoeverFederal University of Uberlândia, Department of Clinical Research, Uberlândia, Minas Gerais, Brazil.
Sophia DuongDivision of Cardiology, University of Toronto, Toronto, Ontario, Canada.
Grace HuangDivision of Cardiology, University of Toronto, Toronto, Ontario, Canada.
Gary TseDepartment of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
Adrian BaranchukDivision of Cardiology, Kingston General Hospital, Queen's University, Kingston, Ontario, Canada.
Benedict M GloverDivision of Cardiology, University of Toronto, Toronto, Ontario, Canada.
International Health Informatics Study (IHIS) Network
University of Toronto · CAChinese University of Hong Kong · CNSecond Hospital of Tianjin Medical University · CNUniversity of Newcastle Australia · AUDalian Medical University · CNKingston General Hospital · CANewcastle University · GBTianjin Medical University · CNUniversidade Federal de Uberlândia · BRUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConventional catheter ablation involves prolonged exposure to ionizing radiation, potentially leading to detrimental health effects. Minimal fluoroscopy (MF) represents a safer alternative, which should be explored. Data on the safety and efficacy of this technique are limited. HYPOTHESIS: Our hypothesis is that MF is of equal efficacy and safety to conventional catheter ablation with the use of fluoroscopy by performing a meta-analysis of both randomized controlled trials (RCTs) and real-world registry studies.

methodsPubmed and Embase were searched from their inception to July 2020 for RCTs, cohort and observational studies that assessed the outcomes of catheter ablation using a MF technique versus the conventional approach.

resultsFifteen studies involving 3795 patients were included in this meta-analysis. There was a significant reduction in fluoroscopy and procedural time with no difference in acute success (odds ratio [OR]:0.74, 95% CI: 0.50-1.10, p = .14), long-term success (OR:0.92, 95% CI: 0.65-1.31, p = .38), arrhythmia recurrence (OR:1.24, 95% CI: 0.75-2.06, p = .97) or rate of complications. (OR:0.83, 95% CI: 0.46-1.48, p = .65). Additionally sub-group analysis for those undergoing catheter ablation for atrial fibrillation (AF) did not demonstrate a difference in success or complication rates (OR:0.86, 95% CI: 0.30-2.42, p = .77). Multivariate meta-regression did not identify the presence of moderator variables.

conclusionThis updated meta-analysis demonstrated an overall reduction in procedural and fluoroscopy time for those undergoing a minimal fluoroscopic approach. There was no significant difference in either acute or chronic success rates or complications between a MF approach and conventional approach for the management of all arrhythmias including those undergoing catheter ablation for AF.

Indexed as

Atrial FibrillationCatheter AblationElectrophysiologic Techniques, CardiacFluoroscopyHumansTreatment Outcomecatheter ablationfluoroscopyradiationX-ray

Identifiers

PMID33998690
PMCPMC8207968
OpenAlexW3161442935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.