ArticleeLife2021
Clustered functional domains for curves and corners in cortical area V4.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Re-emergence of orientation coding in primate IT cortex and deep networks reveals functional hubs for visual processing.bioRxiv : the preprint server for biology · 2026Article
- Multidimensional visual feature encoding and functional organization in the pigeon entopallium.Zoological research · 2026Article
- Local lateral connectivity is sufficient for replicating cortex-like topographical organization in deep neural networks.Nature communications · 2026Article
- Computational constraints underlying shape and texture functional domain organization in macaque V4.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Reproducing the Few-Shot Learning Capabilities of the Visual Ventral Pathway Using Vision Transformers and Neural Fields.Brain sciences · 2025Article
- High-Density Recording Reveals Sparse Clusters (But Not Columns) for Shape and Texture Encoding in Macaque V4.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Heterogeneous orientation tuning in the primary visual cortex of mice diverges from Gabor-like receptive fields in primates.Cell reports · 2024Article
- A ventromedial visual cortical 'Where' stream to the human hippocampus for spatial scenes revealed with magnetoencephalography.Communications biology · 2024Article
- Hue and orientation pinwheels in macaque area V4.Journal of neurophysiology · 2024Article
- Large-scale calcium imaging reveals a systematic V4 map for encoding natural scenes.Nature communications · 2024Article
- High-density recording reveals sparse clusters (but not columns) for shape and texture encoding in macaque V4.bioRxiv : the preprint server for biology · 2023Article
- Genetic Approaches for Neural Circuits Dissection in Non-human Primates.Neuroscience bulletin · 2023Review
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ventral visual pathway is crucially involved in integrating low-level visual features into complex representations for objects and scenes. At an intermediate stage of the ventral visual pathway, V4 plays a crucial role in supporting this transformation. Many V4 neurons are selective for shape segments like curves and corners; however, it remains unclear whether these neurons are organized into clustered functional domains, a structural motif common across other visual cortices. Using two-photon calcium imaging in awake macaques, we confirmed and localized cortical domains selective for curves or corners in V4. Single-cell resolution imaging confirmed that curve- or corner-selective neurons were spatially clustered into such domains. When tested with hexagonal-segment stimuli, we find that stimulus smoothness is the cardinal difference between curve and corner selectivity in V4. Combining cortical population responses with single-neuron analysis, our results reveal that curves and corners are encoded by neurons clustered into functional domains in V4. This functionally specific population architecture bridges the gap between the early and late cortices of the ventral pathway and may serve to facilitate complex object recognition.
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