ArticleJournal of the International Neuropsychological Society : JINS2022
Smartphone-Based Neuropsychological Assessment in Parkinson's Disease: Feasibility, Validity, and Contextually Driven Variability in Cognition.
Article in Journal of the International Neuropsychological Society : JINS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Smartphone-Based Hand Function Assessment: Systematic Review.Journal of medical Internet research · 2024Pooled it
- eHealth tools to assess the neurological function for research, in absence of the neurologist - a systematic review, part I (software).Journal of neurology · 2024Pooled it
- Investigating mechanisms and monitoring outcomes in functional neurological disorder: the unrealized potential of digital remote monitoring technologies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Real-Time Smartphone Monitoring Assessments as a Cognitive Biomarker of Alzheimer Disease: Protocol for a Development Study.JMIR research protocols · 2026Article
- How to advance the pharmacological management of cognitive impairment in Parkinson's disease.Journal of Parkinson's disease · 2026Review
- Development and Preliminary Validation of ORCA-PD, an Online Rapid Cognitive Assessment for Parkinson Disease: Mixed Methods Study.Journal of medical Internet research · 2026Article
- Examining Smartphone-assessed Executive Function Metrics and Intrinsic Resting-State Functional Connectivity in Depression.Research square · 2025Article
- Mobile cognitive remote assessment of schizophrenia: a global multi-site pilot study.Schizophrenia (Heidelberg, Germany) · 2025Article
- Digital health technologies in the accelerating medicines Partnership® Schizophrenia Program.Schizophrenia (Heidelberg, Germany) · 2025Article
- Enhancing neuropsychological assessment clinical pathways in Parkinson's disease through the use of technology.Frontiers in digital health · 2025Article
- Characterizing Performance on a Suite of English-Language NeuroUX Mobile Cognitive Tests in a US Adult Sample: Ecological Momentary Cognitive Testing Study.Journal of medical Internet research · 2024Article
- Dementia and Video Games: Systematic and Bibliographic Review.Healthcare (Basel, Switzerland) · 2024Review
- Mobile Application Applied for Cognitive Rehabilitation: A Systematic Review.Life (Basel, Switzerland) · 2024Review
- Digital Neuropsychology beyond Computerized Cognitive Assessment: Applications of Novel Digital Technologies.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Review
- Capturing learning curves with the multiday Boston Remote Assessment of Neurocognitive Health (BRANCH): Feasibility, reliability, and validity.Neuropsychology · 2024Article
- Online cognitive testing in Parkinson's disease: advantages and challenges.Frontiers in neurology · 2024Review
- Mobile Toolbox sequences task: development and validation of a remote, smartphone-based working memory test.Frontiers in psychology · 2024Article
- A Review on Smartphone Keystroke Dynamics as a Digital Biomarker for Understanding Neurocognitive Functioning.Brain sciences · 2023Review
- A scoping review of neurodegenerative manifestations in explainable digital phenotyping.NPJ Parkinson's disease · 2023Article
- Improving naturalistic neuroscience with patient engagement strategies.Frontiers in human neuroscience · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThe prevalence of neurodegenerative disorders demands methods of accessible assessment that reliably captures cognition in daily life contexts. We investigated the feasibility of smartphone cognitive assessment in people with Parkinson's disease (PD), who may have cognitive impairment in addition to motor-related problems that limit attending in-person clinics. We examined how daily-life factors predicted smartphone cognitive performance and examined the convergent validity of smartphone assessment with traditional neuropsychological tests.
methodsTwenty-seven nondemented individuals with mild-moderate PD attended one in-lab session and responded to smartphone notifications over 10 days. The smartphone app queried participants 5x/day about their location, mood, alertness, exercise, and medication state and administered mobile games of working memory and executive function.
resultsResponse rate to prompts was high, demonstrating feasibility of the approach. Between-subject reliability was high on both cognitive games. Within-subject variability was higher for working memory than executive function. Strong convergent validity was seen between traditional tests and smartphone working memory but not executive function, reflecting the latter's ceiling effects. Participants performed better on mobile working memory tasks when at home and after recent exercise. Less self-reported daytime sleepiness and lower PD symptom burden predicted a stronger association between later time of day and higher smartphone test performance.
conclusionsThese findings support feasibility and validity of repeat smartphone assessments of cognition and provide preliminary evidence of the effects of context on cognitive variability in PD. Further development of this accessible assessment method could increase sensitivity and specificity regarding daily cognitive dysfunction for PD and other clinical populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.