Evidence map›Paper›PMID 33998435›Full record

ArticleJournal of the International Neuropsychological Society : JINS2022

Sex Effects on Mirror Overflow during Finger Tapping in Children with ADHD.

C Chen, K S Rosch, K E Seymour, D Crocetti, E M Mahone, S H Mostofsky

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04421248 (Anomalous Motor System Physiology in Attention Deficit Hyperactivity Disorder), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04421248 phase4recruitingnot on this map

Anomalous Motor System Physiology in Attention Deficit Hyperactivity Disorder: Biomarker Validation and Modeling Domains of Function

TypeinterventionalSponsorDonald Gilbert, MD, MS, FAAN, FAAPRan2020 to 2026Enrolled214ConditionsAttention Deficit Hyperactivity Disorder CombinedArmsMethylphenidate, Placebo
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

C ChenCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.ORCID 0000-0001-8462-1370
K S RoschCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.ORCID 0000-0002-1923-2552
K E SeymourCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.
D CrocettiCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.
E M MahoneDepartment of Neuropsychology, Kennedy Krieger Institute, Baltimore, MD, USA.ORCID 0000-0002-5022-1499
S H MostofskyCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, USA.
Kennedy Krieger Institute · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Stewart H Mostofsky · 2020 to 2026
$9.9M
Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VALLE, DAVID · 2014 to 2019
$7.9M
Neurology of Deficient Response Control in ADHDR01MH085328 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MOSTOFSKY, STEWART H · 2009 to 2019
$7.3M
Anomalous Motor Physiology In ADHDR01MH078160 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MOSTOFSKY, STEWART H · 2006 to 2024
$5.8M
Development of ADHD in Preschool Children: Neuroimaging and Behavioral CorrelatesR01HD068425 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MAHONE, ERNEST MARK · 2012 to 2016
$2.5M
Neurobehavioral Correlates of Frustration in Children with ADHDK23MH107734 · NIMH · JOHNS HOPKINS UNIVERSITY · PI SEYMOUR, KAREN E · 2015 to 2019
$815k
Delay Discounting in Children with ADHD: Neuroimaging and Behavioral CorrelatesK23MH101322 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI ROSCH, KERI SHIELS · 2013 to 2017
$735k
Movement-Based Training for Children with ADHD: A Feasibility StudyR21MH104651 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MOSTOFSKY, STEWART H · 2014 to 2015
$519k
Examination of developmental trajectories of cognitive, motor and emotional control in relation to sex differences in psychopathologyR03MH119457 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI ROSCH, KERI SHIELS · 2020 to 2021
$162k
NICHD NIH HHS P50 HD103538NICHD NIH HHS R01 HD068425NICHD NIH HHS U54 HD079123NIMH NIH HHS K23 MH101322NIMH NIH HHS K23 MH107734NIMH NIH HHS R01 MH078160NIMH NIH HHS R01 MH085328NIMH NIH HHS R03 MH119457NIMH NIH HHS R21 MH104651
6 · The paper itself

Abstract

objectivesThe presence of excessive mirror overflow in children with Attention Deficit/Hyperactivity Disorder (ADHD) is discussed in numerous published reports. These reports, however, include a limited age range in their samples. The objective of this study is to examine the effects of diagnosis and sex on mirror overflow and standard deviation (SD) of tap time in children with and without ADHD across a larger age range (5-12 years) of children.

methodsOne-hundred and forty-eight children with ADHD and 112 age- and sex-matched typically developing (TD) children completed a finger sequencing task. Mirror overflow, SD of tap time, and mean tap time were measured using finger twitch transducers.

resultsResults reveal a significant diagnostic effect on mirror overflow such that boys and girls with ADHD demonstrate increased overflow compared to same-sex TD children. Boys with ADHD demonstrated more variable tap times compared to TD boys; no diagnostic effect was observed in the girls.

conclusionsBoys with ADHD exhibit anomalous motor variability; girls with ADHD show similar levels of variability as TD girls. Boys and girls with ADHD exhibit similar levels of excessive mirror overflow. This lack of sex differences on mirror overflow is distinct from reports finding sex effects on overflow and could result from an examination of a broader age range than is included in prior reports. Adolescent data would provide a greater understanding of the trajectory of anomalous mirror overflow across development. Examination of functional and structural connectivity would expand the current understanding of the neurobiological foundation of motor overflow.

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentChildChild, PreschoolFemaleHumansMaleChild developmental disorderDevelopmental disabilitiesMotor skillsPreschool childrenPsychomotor performanceSchool-age population

Identifiers

PMID33998435
PMCPMC8595312
OpenAlexW3162479490

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.