Evidence map›Paper›PMID 33998292›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2021

Exercise effect on insulin-dependent and insulin-independent glucose utilization in healthy individuals and individuals with type 1 diabetes: a modeling study.

Davide Romeres, Michele Schiavon, Ananda Basu, Claudio Cobelli, Rita Basu, Chiara Dalla Man

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Hyperglycemia Suppresses Lactate Clearance During Exercise in Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Davide RomeresDepartment of Information Engineering, University of Padova, Padova, Italy.
Michele SchiavonDepartment of Information Engineering, University of Padova, Padova, Italy.
Ananda BasuDivision of Endocrinology, University of Virginia School of Medicine, Charlottesville, Virginia.
Claudio CobelliDepartment of Woman and Child's Health, University of Padova, Padova, Italy.
Rita BasuDivision of Endocrinology, University of Virginia School of Medicine, Charlottesville, Virginia.
Chiara Dalla ManDepartment of Information Engineering, University of Padova, Padova, Italy.
University of Padua · ITUniversity of Virginia · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
MECHANISMS OF INSULIN RESISTANCE IN MANR01DK029953 · NIDDK · UNIVERSITY OF VIRGINIA · PI BASU, RITA · 1986 to 2024
$11.5M
Integrated Approaches to Close the Loop in Type 1 DiabetesR01DK085516 · NIDDK · UNIVERSITY OF VIRGINIA · PI BASU, ANANDA · 2009 to 2021
$6.5M
Relative Efficacy of Single-, Bi-, and Tri-Hormonal Closed-Loop Control SystemsDP3DK106785 · NIDDK · UNIVERSITY OF VIRGINIA · PI BASU, ANANDA · 2015 to 2015
$3.5M
Role of Carotid Bodies in Glucose Regulation and Counter Regulation in HumansR01DK090541 · NIDDK · MAYO CLINIC ROCHESTER · PI BASU, RITA · 2011 to 2014
$2.6M
NCATS NIH HHS UL1 TR000135NIDDK NIH HHS DP3 DK106785NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK029953NIDDK NIH HHS R01 DK085516NIDDK NIH HHS R01 DK090541
6 · The paper itself

Abstract

Exercise effects (EE) on whole body glucose rate of disappearance (Rd) occur through insulin-independent (IIRd) and insulin-dependent (IDRd) mechanisms. Quantifying these processes in vivo would allow a better understanding of the physiology of glucose regulation. This is of particular importance in individuals with type 1 diabetes (T1D) since such a knowledge may help to improve glucose management. However, such a model is still lacking. Here, we analyzed data from six T1D and six nondiabetic (ND) subjects undergoing a labeled glucose clamp study during, before, and after a 60-min exercise session at 65% V̇o

Indexed as

AdolescentAdultBlood GlucoseDiabetes Mellitus, Type 1ExerciseGlucose Clamp TechniqueGlycemic ControlHomeostasisHumansInsulinModels, TheoreticalOxygen ConsumptionYoung AdultBlood GlucoseInsulinglucose fluxesmodelphysical activitytracertype 1 diabetes

Identifiers

PMID33998292
PMCPMC8321821
OpenAlexW3163946926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.