Evidence map›Paper›PMID 33998222›Full record

ArticleResearch report (Health Effects Institute)2021

Novel Mechanisms of Ozone-Induced Pulmonary Inflammation and Resolution, and the Potential Protective Role of Scavenger Receptor BI.

K M Gowdy, B Kilburg-Basnyat, M X Hodge, S W Reece, V Yermalitsk, S S Davies, J Manke, M L Armstrong, N Reisdorph, R M Tighe and 1 more

Open access · greenAbstract read
In one paragraph

Article in Research report (Health Effects Institute), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Aerosol physicochemical determinants of carbon black and ozone inhalation co-exposure induced pulmonary toxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

K M GowdyDepartment of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
B Kilburg-BasnyatDepartment of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
M X HodgeDepartment of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
S W ReeceDepartment of Pharmacology & Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
V YermalitskDivision of Clinical Pharmacology, Department of Pharmacology, Vanderbilt University, Nashville, Tennessee.
S S DaviesDivision of Clinical Pharmacology, Department of Pharmacology, Vanderbilt University, Nashville, Tennessee.
J MankePharmaceutical Science, University of Colorado School of Medicine, Aurora, Colorado.
M L ArmstrongPharmaceutical Science, University of Colorado School of Medicine, Aurora, Colorado.
N ReisdorphPharmaceutical Science, University of Colorado School of Medicine, Aurora, Colorado.
R M TigheDepartment of Medicine, Duke University Medical Center, Durham, North Carolina.
S R ShaikhDepartment of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina, Chapel Hill.
East Carolina University · USDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncreases in ambient levels of ozone (O SPECIFIC

aimsThe primary goals of this study were: Aim 1 - to define the role of SR-BI in O

methodsTo address Aim 1, female wild-type (WT) and SR-BI-deficient, or knock-out (SR-BI KO), mice were exposed to either O To address Aim 2, male WT mice were exposed to either O

resultsFor Aim 1, SR-BI protein levels increased in the lung tissue of mice exposed to O For Aim 2, mice given SPM supplementation before O

conclusionsOur findings identify novel mechanisms by which O

Indexed as

AnimalsInhalation ExposureMiceOzonePneumoniaReceptors, ScavengerOzoneReceptors, Scavenger

Identifiers

PMID33998222
PMCPMC8126671
OpenAlexW3160281958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.