ArticleActa ophthalmologica2022
Epiretinal large disc of blue-stained lyophilized amniotic membrane to treat complex macular holes: a 1-year follow-up.
Article in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Optimal approaches for managing recurrent macular holes: a comprehensive systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Amniotic membrane transplantation for macular holes: decoding the optimal approach-inlay or overlay?International ophthalmology · 2025Pooled it
- Surgical Outcomes of Epiretinal Human Amniotic Membrane Transplantation for Refractory Macular Holes.Journal of clinical medicine · 2026Article
- Precut disc of lyophilized amniotic membrane for recurrent full thickness macular hole management.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Reply on comments on the paper "Descemet's membrane transplantation for the treatment of recurrent high myopic macular hole associated with retinal detachment".Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Letter to the editor regarding "Descemet's membrane transplantation for the treatment of recurrent high myopic macular hole associated with retinal detachment".Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Letter to the Editor regarding "Biological ultrathin amniotic membrane flap to close refractory macular holes associated with high myopia".Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Safety and efficacy of human amniotic membrane plug transplantation in cases of macular hole. A scoping review.International journal of retina and vitreous · 2024Article
- Human Amniotic Membrane: A Seal for Complex Retinal Detachments.Turkish journal of ophthalmology · 2024Article
- A Novel Technique Using Lyophilized Amniotic Membrane Patch (LAMPatch) as Primary Procedure in Patients with Myopic Traction Maculopathy with Macular Detachment.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Epiretinal implant of human amniotic membrane to treat highly myopic macular hole retinal detachments: A novel surgical technique.European journal of ophthalmology · 2024Article
- The developments in amniotic membrane transplantation in glaucoma and vitreoretinal procedures.International ophthalmology · 2023Review
- Femtosecond laser-cut autologous anterior lens capsule transplantation to treat refractory macular holes.Eye (London, England) · 2023Article
- Comment on: Amniotic membrane for covering high myopic macular hole associated with retinal detachment following failed primary surgery.International journal of ophthalmology · 2023Article
- Anatomical, functional outcomes, and complications of human amniotic membrane graft for macular hole: A systematic review.Taiwan journal of ophthalmologyReview
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3 authors.
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Abstract
purposeTo report the long-term outcomes of large diameter epiretinal lyophilized amniotic membranes (lAMs) in recurrent or persistent macular holes (MHs) with or without rhegmatogenous retinal detachment (RRD), in a prospective interventional case series.
methodsTen eyes of 10 patients underwent pars plana vitrectomy for MH-associated RRD (n = 5) or persistent MH without RRD (n = 5), in a university Hospital. A 3 or 4 mm diameter disc of lAM, stained with 0.06% trypan blue, was inserted with a catheter through a sclerotomy and positioned over the MH. Gas or silicone-oil tamponade was used. At 1 year, the main outcome was anatomic success defined as complete MH closure. Secondary outcomes were best corrected visual acuity (BCVA) recovery, changes in ellipsoid zone (EZ) and external limiting membrane (ELM) defects, complications. Mean follow-up was 13.8 ± 2.9 months (range, 12-18).
resultsMean baseline data were minimum and maximum diameters, respectively, 945 ± 330 and 1507 ± 717 μm; axial length 26.58 ± 3.38 mm; and number of prior surgeries 1.4 ± 0.96. At 1 year, anatomic success was achieved in eight eyes (80%), and two had reduced diameter of MH. All RRDs were reattached without recurrence. Mean logMAR BCVA improved from 1.92 ± 0.58 to 1.17 ± 0.57 (p < 0.001), with nine eyes (90%) achieving ≥0.3 logMAR improvement. Mean EZ and ELM defects decreased (p = 0.004, p = 0.003, respectively). Postoperative complications were RRD (n = 1) reattached by subsequent surgery, lAM slightly retracted under silicone (n = 1), foveal atrophy after early lAM displacement (n = 1).
conclusionA 1-year follow-up highlighted that epiretinal large discs of blue-stained lAM can help safely close refractory MHs, and provide satisfactory visual recovery.
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