Evidence map›Paper›PMID 33998125›Full record

Observational studyBJOG : an international journal of obstetrics and gynaecology2021

Impact of severe acute respiratory syndrome coronavirus 2 on ectopic pregnancy management in the United Kingdom: a multicentre observational study.

S Platts, J Ranawaka, R Oliver, S Patra-Das, P Kotabagi, C Neophytou, N Shah, M Toal, P Bassett, A Davison and 5 more

Open access · bronzeAbstract readComparative StudyMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BJOG : an international journal of obstetrics and gynaecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

S PlattsDepartment of Obstetrics and Gynaecology, Whipps Cross University Hospital, Barts Health Trust, London, UK.ORCID 0000-0002-8723-6993
J RanawakaDepartment of Obstetrics and Gynaecology, Whipps Cross University Hospital, Barts Health Trust, London, UK.
R OliverDepartment of Obstetrics and Gynaecology, Whipps Cross University Hospital, Barts Health Trust, London, UK.
S Patra-DasDepartment of Obstetrics and Gynaecology, Homerton University Hospital, London, UK.
P KotabagiDepartment of Obstetrics and Gynaecology, North Middlesex University Hospital, London, UK.
C NeophytouDepartment of Obstetrics and Gynaecology, Royal London Hospital, Barts Health NHS Trust, London, UK.
N ShahDepartment of Obstetrics and Gynaecology, Newham Hospital, Barts Health NHS Trust, London, UK.ORCID 0000-0001-7540-3179
M ToalDepartment of Obstetrics and Gynaecology, Homerton University Hospital, London, UK.
P BassettStatsconsultancy Ltd, Amersham, Buckinghamshire, UK.
A DavisonDepartment of Obstetrics and Gynaecology, Homerton University Hospital, London, UK.
M GbegbajeDepartment of Obstetrics and Gynaecology, Royal London Hospital, Barts Health NHS Trust, London, UK.
K RaoDepartment of Obstetrics and Gynaecology, Newham Hospital, Barts Health NHS Trust, London, UK.
S RouabhiDepartment of Obstetrics and Gynaecology, North Middlesex University Hospital, London, UK.
S WatsonDepartment of Obstetrics and Gynaecology, Homerton University Hospital, London, UK.
F OdejinmiDepartment of Obstetrics and Gynaecology, Whipps Cross University Hospital, Barts Health Trust, London, UK.
Barts Health NHS Trust · GBHomerton University Hospital · GBWhipps Cross University Hospital · GBNorth Middlesex Hospital · GBAmersham Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the impact of coronavirus disease 2019 (COVID-19) on the management of women with ectopic pregnancy.

designA multicentre observational study comparing outcomes from a prospective cohort during the pandemic [COVID-19-ectopic pregnancy registry (CEPR)] compared with a historical pre-pandemic cohort [non-COVID-19-ectopic pregnancy registry (NCEPR)].

settingFive London university hospitals. POPULATION AND

methodsConsecutive patients diagnosed clinically and/or radiologically with ectopic pregnancy (March 2020-August 2020) were entered into the CEPR and results were compared with the NCEPR cohort (January 2019-June 2019). An adjusted analysis was performed for potentially confounding variables.

main outcome measuresPatient demographics, management (expectant, medical and surgical), length of treatment, number of hospital visits (non-surgical management), length of stay (surgical management) and 30-day complications.

resultsThree hundred and forty-one women met the inclusion criteria: 162 CEPR and 179 NCEPR. A significantly lower percentage of women underwent surgical management versus non-surgical management in the CEPR versus NCEPR (58.6%; 95/162 versus 72.6%; 130/179; P = 0.007). Among patients managed with expectant management, the CEPR had a significantly lower mean number of hospital visits compared with NCEPR (3.0, interquartile range [IQR] [3, 5] versus 9.0, [5, 14]; P = <0.001). Among patients managed with medical management, the CEPR had a significantly lower median number of hospital visits versus NCEPR (6.0, [5, 8] versus 9, [6, 10]; P = 0.003). There was no observed difference in complication rates between cohorts.

conclusionWomen were found to undergo significantly higher rates of non-surgical management during the COVID-19 first wave compared with a pre-pandemic cohort. Women managed non-surgically in the CPER cohort were also managed with fewer hospital attendances. This did not lead to an increase in observed complication rates. TWEETABLE ABSTRACT: A higher rate of non-surgical management of ectopic pregnancy during the COVID-19 pandemic did not increase complication rates.

Indexed as

AdultCOVID-19FemaleHumansPandemicsPregnancyPregnancy, EctopicProspective StudiesRegistriesSARS-CoV-2United KingdomWatchful Waitingcoronavirus disease 2019fallopian tubesmethotrexate/therapeutic usepregnancy, ectopic

Identifiers

PMID33998125
PMCPMC8209857
OpenAlexW3160371466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.