ArticlePlant cell reports2021
A salicylic acid inducible mulberry WRKY transcription factor, MiWRKY53 is involved in plant defence response.
Article in Plant cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Histone demethylase CsJMJ12 enhances resistance of Navel orange to Penicillium digitatum via H3K27me3 demethylation.Journal of advanced research · 2026Article
- Discovery of a defence-response gene forFrontiers in plant science · 2026Article
- Strengths and Limitations of Salicylic Acid Reporters.International journal of molecular sciences · 2025Review
- Genome-wide identification and characterization of WRKYs family involved in responses to Cylindrocarpon destructans in Panax notoginseng.BMC genomics · 2025Article
- Plant Coping with Cold Stress: Molecular and Physiological Adaptive Mechanisms with Future Perspectives.Cells · 2025Review
- Genome-wide identification of WRKY gene family and expression analysis of keyFrontiers in plant science · 2025Article
- Advances in WRKY regulation of immune responses in medicinal plants.Frontiers in plant science · 2025Review
- A novel protein elicitor (Cs08297) from Ciboria shiraiana enhances plant disease resistance.Molecular plant pathology · 2024Article
- Refinement and Enhancement ofGenes · 2024Article
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- Identification ofPlants (Basel, Switzerland) · 2024Article
- Recent advances in functional assays of WRKY transcription factors in plant immunity against pathogens.Frontiers in plant science · 2024Review
- The role of WRKY transcription factors, FaWRKY29 and FaWRKY64, for regulating Botrytis fruit rot resistance in strawberry (Fragaria × ananassa Duch.).BMC plant biology · 2023Article
- Identification and Characterization ofInternational journal of molecular sciences · 2022Article
- Article
- Changes in the expression level of genes encoding transcription factors and cell wall-related proteins during Meloidogyne arenaria infection of maize (Zea mays).Molecular biology reports · 2021Article
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Authors and funding
2 authors.
Funding
Abstract
key messageMiWRKY53 is expressed in response to various stresses and hormones. Although it is localized in the nucleus, it shows no transcriptional activation. Role of SA-mediated plant defence response is demonstrated. WRKY transcription factors are one the largest gene families in plants involved in almost every process in plants including development, physiological processes, and stress response. Salicylic acid (SA) is key regulator of biotic stress against various pathogens in plants acting via its multiple mechanisms to induce defence response. Herein, we have identified and functionally validated WRKY53 from mulberry (Morus indica var. K2). MiWRKY53 expressed differentially in response to different stress and hormonal treatments. MiWRKY53 belongs to group III of WKRY gene family, localized in nucleus, and lacks transcriptional activation activity in yeast. Hormone responsive behaviour of MiWRKY53 Arabidopsis overexpression (OE) transgenics preferentially was noted in root growth assay in response to Salicylic acid (SA). Arabidopsis overexpression plants also displayed alteration in leaf phenotype having wider leaves than the wild-type plants. PR-1 transcripts were higher in MiWRKY53 Arabidopsis OE plants and they displayed resistance towards biotrophic pathogen Pseudomonas syringae PstDC3000. MiWRKY53 Mulberry OE transgenics also depicted SA-responsive behaviour. Several hormones and stress-related cis-acting elements were also identified in the 1.2-Kb upstream regulatory region (URR) of MiWRKY53. Functional characterization of full-length promoter region revealed that it is induced by SA and further analysis of deletion constructs helped in the identification of minimal promoter responsible for its inducibility by SA. Altogether, the findings from this study point towards the SA preferential behaviour of MiWRKY53 and its function as regulator of plant defence response through SA-mediated mechanisms.
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