ArticleEClinicalMedicine2021
Global economic productivity losses from vision impairment and blindness.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 15 of them syntheses that pooled it.
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Who cites it
109 citing papers in PubMed, 15 syntheses or guidelines pooled it, 209 citations in OpenAlex.
- Clinical efficacy and safety of anti-VEGF biosimilars compared to reference anti-VEGF agents for neovascular age-related macular degeneration: a systematic review, meta-analysis, and meta-regression.International ophthalmology · 2026Pooled it
- The prevalence of diabetic retinopathy in type-2 diabetes in Pakistan: a systematic review and meta-analysis.Frontiers in clinical diabetes and healthcare · 2026Pooled it
- Effectiveness of low vision rehabilitation on visual function and quality of life in Sub-Saharan Africa: a systematic review.Frontiers in rehabilitation sciences · 2026Pooled it
- Prevalence, burden, and determinants of visual impairment and blindness among adults in Saudi Arabia: a comprehensive systematic review and meta-analysis.BMC ophthalmology · 2025Pooled it
- Prevalence of vision impairment among patients with diabetes mellitus in sub-Saharan Africa: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Prevalence of clinically significant refractive error in children in Europe: Systematic review and meta-analysis.PloS one · 2025Pooled it
- Eye health promotion in multi-sectoral settings: A systematic review of intervention types and effectiveness.F1000Research · 2025Pooled it
- Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020.Eye (London, England) · 2024Pooled it
- Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020.Eye (London, England) · 2024Pooled it
- Anti-vascular endothelial growth factor biosimilars for neovascular age-related macular degeneration.The Cochrane database of systematic reviews · 2024Pooled it
- The effects of age-related macular degeneration on work productivity: A meta-analysis.European journal of ophthalmology · 2024Pooled it
- Cost-of-illness studies of inherited retinal diseases: a systematic review.Orphanet journal of rare diseases · 2024Pooled it
- The case for investment in eye health: systematic review and economic modelling analysis.Bulletin of the World Health Organization · 2023Pooled it
- Pooled it
- DoesJournal of evidence-based integrative medicinePooled it
- Improving knowledge and attitudes via an interactive video: A randomized controlled trial.Rehabilitation psychology · 2026Trial
- Gene therapy induces synaptic ribbon maturation, synaptogenesis and vision recovery in an adult dog model of retinal degeneration.Molecular therapy. Advances · 2026Article
- Exploring variations in Certificate of Vision Impairment (CVI) with geographical locations, deprivation indices, density of optometry practices and number of older people living in Mid and South Essex: an analysis of publicly available data.Eye (London, England) · 2026Article
- Direct and indirect costs associated with declining distance visual acuity: A nationwide longitudinal cost-of-illness study with 11-year follow-up.Acta ophthalmologica · 2026Observational
- An economic analysis of postoperative cataract consultation using remote self-assessment.PLOS digital health · 2026Article
49 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors at 10 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the absence of accessible, good quality eye health services and inclusive environments, vision loss can impact individuals, households and communities in many ways, including through increased poverty, reduced quality of life and reduced employment. We aimed to estimate the annual potential productivity losses associated with reduced employment due to blindness and moderate and severe vision impairment (MSVI) at a regional and global level.
methodsWe constructed a model using the most recent economic, demographic (2018) and prevalence (2020) data. Calculations were limited to the working age population (15-64 years) and presented in 2018 US Dollars purchasing power parity (ppp). Two separate models, using Gross Domestic Product (GDP) and Gross National Income (GNI), were calculated to maximise comparability with previous estimates.
findingsWe found that 160.7 million people with MSVI or blindness were within the working age and estimated that the overall relative reduction in employment by people with vision loss was 30.2%. Globally, using GDP we estimated that the annual cost of potential productivity losses of MSVI and blindness was $410.7 billion ppp (range $322.1 - $518.7 billion), or 0.3% of GDP. Using GNI, overall productivity losses were estimated at $408.5 billion ppp (range $320.4 - $515.9 billion), 0.5% lower than estimates using GDP.
interpretationThese findings support the view that blindness and MSVI are associated with a large economic impact worldwide. Reducing and preventing vision loss and developing and implementing strategies to help visually impaired people to find and keep employment may result in significant productivity gains.
fundingMJB is supported by the Wellcome Trust (207472/Z/17/Z). JR's appointment at the University of Auckland is funded by the Buchanan Charitable Foundation, New Zealand. The
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.