Evidence map›Paper›PMID 33997730›Full record

ArticleEClinicalMedicine2021

The relationship of large city out-of-hospital cardiac arrests and the prevalence of COVID-19.

Kevin E McVaney, Paul E Pepe, Lauren M Maloney, E Stein Bronsky, Remle P Crowe, James J Augustine, Sheaffer O Gilliam, Glenn H Asaeda, Marc Eckstein, Amal Mattu and 4 more

Open access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Emergency medical services clinicians in the United States are increasingly exposed to death.Journal of the American College of Emergency Physicians open · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Death by COVID-19: An Open Investigation.Journal of the American Heart Association · 2021
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

Kevin E McVaneyDepartment of Emergency Medicine, University of Colorado School of Medicine, Denver, CO, USA.
Paul E PepeDallas County Emergency Medical Services and County Public Safety Agencies, Dallas, TX, USA.
Lauren M MaloneyDepartment of Emergency Medicine, Stony Brook University Hospital, Stony Brook, NY, USA.
E Stein BronskyColorado Springs Fire Department, Colorado Springs, CO, USA.
Remle P CroweESO, Austin, TX, USA.
James J AugustineWright State University, Dayton, OH, USA.
Sheaffer O GilliamDepartment of Emergency Medicine, University of Colorado School of Medicine, Denver, CO, USA.
Glenn H AsaedaFire Department of New York, New York, NY, USA.
Marc EcksteinLos Angeles Fire Department, Los Angeles, CA, USA.
Amal MattuUniversity of Maryland, Baltimore, MD, USA.
Roberto FumagalliNiguarda Hospital, University of Milano-Bicocca, Milan, Italy.
Tom P AufderheideResuscitation Research Center, Medical College of Wisconsin, Milwaukee, WI, USA.
Michael T OsterholmUniversity of Minnesota Center for Infectious Disease Research and Policy, Minneapolis, MN, USA.
Writing group on behalf of the Metropolitan EMS Medical Directors Global Alliance
Denver Health Medical Center · USNew York City Fire Department · USAgenzia Regionale Emergenza Urgenza · ITDallas County · USMedical College of Wisconsin · USStony Brook University Hospital · USUniversity of Maryland, Baltimore · USUniversity of Minnesota · USUniversity of Southern California · USWright State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThough variable, many major metropolitan cities reported profound and unprecedented increases in out-of-hospital cardiac arrest (OHCA) in early 2020. This study examined the relative magnitude of those increases and their relationship to COVID-19 prevalence.

methodsEMS (9-1-1 system) medical directors for 50 of the largest U.S. cities agreed to provide the aggregate, de-identified, pre-existing monthly tallies of OHCA among adults (age >18 years) occurring between January and June 2020 within their respective jurisdictions. Identical comparison data were also provided for corresponding time periods in 2018 and 2019.  Equivalent data were obtained from the largest cities in Italy, United Kingdom and France, as well as Perth, Australia and Auckland, New Zealand.

findingsSignificant OHCA escalations generally paralleled local prevalence of COVID-19. During April, most U.S. cities (34/50) had >20% increases in OHCA versus 2018-2019 which reflected high local COVID-19 prevalence. Thirteen observed 1·5-fold increases in OHCA and three COVID-19 epicenters had >100% increases (2·5-fold in New York City). Conversely, cities with lesser COVID-19 impact observed unchanged (or even diminished) OHCA numbers. Altogether (

interpretationMost metropolitan cities experienced profound escalations of OHCA generally paralleling local prevalence of COVID-19.  Most of these patients were pronounced dead without COVID-19 testing.

fundingNo funding was involved. Cities provided de-identified aggregate data collected routinely for standard quality assurance functions.

Identifiers

PMID33997730
PMCPMC8102707
OpenAlexW3148068422

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.