Evidence map›Paper›PMID 33997702›Full record

ArticleiScience2021

Immunogenic tumor cell death promotes dendritic cell migration and inhibits tumor growth via enhanced T cell immunity.

Taiki Moriya, Kurumi Kitagawa, Yuuki Hayakawa, Hiroaki Hemmi, Tsuneyasu Kaisho, Satoshi Ueha, Ryoyo Ikebuchi, Ippei Yasuda, Yasutaka Nakanishi, Tetsuya Honda and 6 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 46 citations in OpenAlex.

  1. CD4Oncoimmunology · 2026
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  13. CanPharmaceuticals (Basel, Switzerland) · 2025
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  17. The battle within: cell death by phagocytosis in cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Taiki MoriyaLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Kurumi KitagawaLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Yuuki HayakawaLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Hiroaki HemmiDepartment of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Graduate school of Medicine, Wakayama, Wakayama 641-8509, Japan.
Tsuneyasu KaishoDepartment of Immunology, Institute of Advanced Medicine, Wakayama Medical University, Graduate school of Medicine, Wakayama, Wakayama 641-8509, Japan.
Satoshi UehaDivision of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda City Chiba 278-0022, Japan.
Ryoyo IkebuchiLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Ippei YasudaLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Yasutaka NakanishiLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Tetsuya HondaDepartment of Dermatology, Kyoto University, Graduate School of Medicine, Sakyou-ku, Kyoto 606-8507, Japan.
Koji MatsushimaDivision of Molecular Regulation of Inflammatory and Immune Diseases, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda City Chiba 278-0022, Japan.
Kenji KabashimaDepartment of Dermatology, Kyoto University, Graduate School of Medicine, Sakyou-ku, Kyoto 606-8507, Japan.
Mizuki UedaLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Yutaka KusumotoLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Tatyana ChtanovaImmunology Theme, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.
Michio TomuraLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka 584-8540, Japan.
Osaka Ohtani University · JPKyoto University · JPTokyo University of Science · JPWakayama Medical University · JPGarvan Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunogenic tumor cell death enhances anti-tumor immunity. However, the mechanisms underlying this effect are incompletely understood. We established a system to induce tumor cell death

Indexed as

CancerCell BiologyImmunology

Identifiers

PMID33997702
PMCPMC8102907
OpenAlexW3153642269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.