Evidence map›Paper›PMID 33997530›Full record

ArticleClinical neurophysiology practice2021

24-Hour video EEG in the evaluation of the first unprovoked seizure.

Naim Haddad, Gayane Melikyan, Gonzalo Alarcon, Yanal Shaheen, Maria Siddiqi, Elfateh Ali, Boulenouar Mesraoua, Hassan AlHail, Abdulaziz Al-Abdulghani, Abdulraheem Alrabi and 3 more

Abstract read
In one paragraph

Article in Clinical neurophysiology practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. 24-Hour Video EEG in the Evaluation of the Seizure-Free Patient Before Antiseizure Medication Withdrawal.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Naim HaddadHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Gayane MelikyanHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Gonzalo AlarconHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Yanal ShaheenWeill Cornell Medicine-Qatar, PO Box 24144, Education City, Doha, Qatar.
Maria SiddiqiHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Elfateh AliHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Boulenouar MesraouaHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Hassan AlHailHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Abdulaziz Al-AbdulghaniWeill Cornell Medicine-Qatar, PO Box 24144, Education City, Doha, Qatar.
Abdulraheem AlrabiHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Anitha SyamalaHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Farhana KaziHamad Medical Corporation, PO Box 3050, Doha, Qatar.
Ziyad MahfoudWeill Cornell Medicine-Qatar, PO Box 24144, Education City, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the gain in detection of epileptiform abnormalities in 24-hour EEG recordings following the first seizure.

methodsWe identified patients who underwent 24-hour video EEG (VEEG) with "first seizure" as an indication. We noted the presence or absence of epileptiform discharges (EDs) in the VEEG study and the latency for the appearance of such discharges. We compared the rate of EDs during the initial 60 min with those occurring only later during the recording.

resultsData from 25 patients, aged 15 to 59, were included. Of the 11 patients with EDs, eight (73%) appeared only after 60 min of recording. This equates to a 32% absolute increase in the detection of EDs across all patients. The latency to first EDs varied from one to 1080 min with a median of 170 min. In four cases, actual subtle seizures were recorded.

conclusionThis study suggests an increase in the detection of EDs with the 24-hour studies compared to the traditional shorter recordings, in the context of a first seizure. SIGNIFICANCE: A standard EEG can be performed close to the seizure, followed by a longer up to 24-hour recording if the initial shorter study is unrevealing.

Indexed as

24-Hour video EEGDiagnostic yieldEDs, epileptiform dischargesEpilepsyEpileptiform dischargesFirst unprovoked seizureVEEG, Video EEG

Identifiers

PMID33997530
PMCPMC8089767

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.