Evidence map›Paper›PMID 33997524›Full record

ReviewJACC. Basic to translational science2021

Conduits' Biology Regulates the Outcomes of Coronary Artery Bypass Grafting.

Lara Gharibeh, Giovanni Ferrari, Mireille Ouimet, Juan B Grau

Abstract readReview
In one paragraph

Review in JACC. Basic to translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Effects of TNF-Journal of clinical medicine · 2026
    Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis.Molecular therapy. Methods & clinical development · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lara GharibehDivision of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Giovanni FerrariDepartment of Surgery and Biomedical Engineering, Columbia University, New York, New York, USA.
Mireille OuimetDivision of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Juan B GrauDivision of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery bypass graft (CABG) is the gold standard for coronary surgical revascularization. Retrospective, prospective, and meta-analysis studies looking into long-term outcomes of using different conduits have pointed to the superiority of arterial grafts over veins and have placed the internal mammary artery as the standard conduit of choice for CABG. The superiority of the internal mammary artery over other conduits could be attributable to its intrinsic characteristics; however, little is known regarding the features that render some conduits atherosclerosis-prone and others atherosclerosis-resistant. Here, an overview is provided of the available data on the most commonly used conduits in CABG (internal mammary artery, saphenous vein, radial artery, gastroepiploic artery), highlighting the differences in their cellular biology, mechanical, biochemical, and vasoconstrictive properties. This information should help in furthering our understanding of the clinical outcomes observed for each of these conduits.

Indexed as

CABG, coronary artery bypass graftcoronary artery bypass graftcoronary artery diseaseEC, endothelial cellECM, extracellular matrixgastroepiploic arteryGEA, gastroepiploic arteryIMA, internal mammary arteryinternal mammary arteryLAD, left anterior descending arteryradial arteryRA, radial arterysaphenous vein graftSVG, saphenous vein graftVSMC, vascular smooth muscle cell

Identifiers

PMID33997524
PMCPMC8093468

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.