Evidence map›Paper›PMID 33997492›Full record

ArticleBioactive materials2021

Ca

Zhanrong Li, Xingcai Zhang, Jiang Ouyang, Dandan Chu, Fengqi Han, Liuqi Shi, Ruixing Liu, Zhihua Guo, Grace X Gu, Wei Tao and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Application and progress of 3D printed biomaterials in osteoporosis.Frontiers in bioengineering and biotechnology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Zhanrong LiHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Xingcai ZhangSchool of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02138, United States.
Jiang OuyangCenter for Nanomedicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States.
Dandan ChuHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Fengqi HanHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Liuqi ShiHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Ruixing LiuHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Zhihua GuoHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Grace X GuDepartment of Mechanical Engineering, University of California, Berkeley, CA, 94720-1740, United States.
Wei TaoCenter for Nanomedicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States.
Lin JinHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.
Jingguo LiHenan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, 450003, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective osteogenesis remains a challenge in the treatment of bone defects. The emergence of artificial bone scaffolds provides an attractive solution. In this work, a new biomineralization strategy is proposed to facilitate osteogenesis through sustaining supply of nutrients including phosphorus (P), calcium (Ca), and silicon (Si). We developed black phosphorus (BP)-based, three-dimensional nanocomposite fibrous scaffolds via microfluidic technology to provide a wealth of essential ions for bone defect treatment. The fibrous scaffolds were fabricated from 3D poly (l-lactic acid) (PLLA) nanofibers (3D NFs), BP nanosheets, and hydroxyapatite (HA)-porous SiO

Indexed as

Artificial bone scaffoldBiomineralizationBlack phosphorusBone defectOsteogenesis

Identifiers

PMID33997492
PMCPMC8089774

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.