Evidence map›Paper›PMID 33997394›Full record

ArticleHeliyon2021

Researchers views about perceived harms and benefits of gene editing: A study from the MENA region.

Sawsan Abuhammad, Omar F Khabour, Karem H Alzoubi

Abstract read
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sawsan AbuhammadDept. of Maternal and Child Health, Jordan University of Science and Technology, Irbid 22110, Jordan.
Omar F KhabourDept. of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.
Karem H AlzoubiDept. of Clinical Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.

Funding

The Research Ethics Education Program in JordanR25TW010026 · FIC · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AL-DELAIMY, WAEL K · 2015 to 2025
$2.5M
FIC NIH HHS R25 TW010026
6 · The paper itself

Abstract

backgroundThe development of gene editing technologies is very promising for the treatment of genetic diseases. However, gene editing can be also used to enhance the characteristics of healthy individuals. This study aims to determine ethical challenges that may face the constitution of gene editing in the Middle East and North Africa (MENA) region.

methodsAn online discussion forum about the ethical challenges of applying gene editing technologies was held. The participants were a group of researchers (n = 28) from the MENA region.

resultsMost of the participants agreed on the importance of gene editing for the treatment of genetic diseases. However, participants had concerns regarding the use of gene editing to enhance the characteristics of healthy individuals such as athletic abilities and intelligence. Among ethical issues that were raised are justice, harm, beneficence, discrimination, conflict with religion and culture, and lack of regulations.

conclusionSeveral ethical issues were raised for using gene editing technologies based on the perception of biomedical researchers from the MENA region. Therefore, the scientific community and other interested bioethical, social, legal, and governmental parties should be provided with a detailed guide from the scientists in this area for future uses of this technology.

Indexed as

EnhancementEthicsGene editingGene therapyMENA

Identifiers

PMID33997394
PMCPMC8095113

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.