ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2021
An overview of aflatoxin B1 biotransformation and aflatoxin M1 secretion in lactating dairy cows.
Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 113 citations in OpenAlex.
- Review
- Article
- Quantifying milk yield-dependent aflatoxin B1-to-M1 transfer in dairy cows: a Bayesian consensus toxicokinetic model.Archives of toxicology · 2026Article
- The Aflatoxin M1 Content of Cow Milk in Cyprus as Affected by Season and Year of Production: A Five-Year Survey.Foods (Basel, Switzerland) · 2026Article
- Nanofabricated essential oils as a green antifungal agent for the management of aflatoxin BArchives of microbiology · 2026Review
- Ultrasensitive on-site detection of aflatoxin MScientific reports · 2026Article
- The health risk assessment and determination of aflatoxin MFood chemistry: X · 2026Article
- Fungal Contamination of Dairy Feed and Major Mycotoxin Transfer: A Risk Evaluation for Animal Exposure and Health.Toxins · 2026Article
- Structure Elucidation and Toxicity Analyses of the Degradation Products of Aflatoxin BJournal of fungi (Basel, Switzerland) · 2026Article
- Mechanistic evidence and assumptions in mycotoxin-gut interaction.Frontiers in fungal biology · 2026Article
- Effect of replacing concentrate diet with oat brewery waste on enteric methane emissions, nutrients intake, digestibility and compositional and functional abundances of rumen microbiota in growing male sheep.Frontiers in microbiology · 2026Article
- Smart Probiotic Solutions for Mycotoxin Mitigation: Innovations in Food Safety and Sustainable Agriculture.Probiotics and antimicrobial proteins · 2026Review
- Space-Confined Hydrogel Particle-Based Biosensor for Early Warning of Aflatoxin B1 via Rapid Label-Free Fluorescence Detection of theAnalytical chemistry · 2025Article
- Aflatoxin Exposure in Immunocompromised Patients: Current State and Future Perspectives.Toxins · 2025Review
- Occurrence of Aflatoxin MToxins · 2025Article
- Exposure of pregnant and lactating parental mice to aflatoxin BArchives of toxicology · 2025Article
- Review
- Article
- Lactic acid bacteria: beyond fermentation to bio-protection against fungal spoilage and mycotoxins in food systems.Frontiers in microbiology · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Milk is considered a perfect natural food for humans and animals. However, aflatoxin B1 (AFB1) contaminating the feeds fed to lactating dairy cows can introduce aflatoxin M1 (AFM1), the main toxic metabolite of aflatoxins into the milk, consequently posing a risk to human health. As a result of AFM1 monitoring in raw milk worldwide, it is evident that high AFM1 concentrations exist in raw milk in many countries. Thus, the incidence of AFM1 in milk from dairy cows should not be underestimated. To further optimize the intervention strategies, it is necessary to better understand the metabolism of AFB1 and its biotransformation into AFM1 and the specific secretion pathways in lactating dairy cows. The metabolism of AFB1 and its biotransformation into AFM1 in lactating dairy cows are drawn in this review. Furthermore, recent data provide evidence that in the mammary tissue of lactating dairy cows, aflatoxins significantly increase the activity of a protein, ATP-binding cassette super-family G member 2 (ABCG2), an efflux transporter known to facilitate the excretion of various xenobiotics and veterinary drugs into milk. Further research should focus on identifying and understanding the factors that affect the expression of ABCG2 in the mammary gland of cows.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.