Evidence map›Paper›PMID 33997091›Full record

ArticleACG case reports journal2021

Lower Gastrointestinal Bleeding Associated With Sodium Polystyrene Sulfonate Use.

Eduardo Dantas, Mariana Coelho, Cristiana Sequeira, Inês Santos, Cláudio Martins, Cláudia Cardoso, Ricardo Freire, Ana Paula Oliveira

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ACG case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eduardo DantasGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Mariana CoelhoGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Cristiana SequeiraGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Inês SantosGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Cláudio MartinsGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Cláudia CardosoGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Ricardo FreireGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Ana Paula OliveiraGastroenterology Department, Centro Hospitalar de Setúbal, Setúbal, Portugal.
Hospital de São Bernardo · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium polystyrene sulfonate (kayexalate) is a cation-exchange resin widely used in the management of hyperkalemia. Gastrointestinal adverse events are uncommon; symptoms are nonspecific, and mucosal injury can range from mild ulceration to bowel perforation. An 81-year-old man was admitted because of decompensation of cirrhosis with acute kidney injury and hyperkalemia, treated with sodium polystyrene sulfonate. During admission, he presented multiple episodes of hematochezia, accompanied by tachycardia and hemoglobin drop. Colonoscopy revealed colonic ulceration, and histopathological findings were compatible with ulceration due to kayexalate injury. Despite rare, the widespread use of sodium polystyrene sulfonate puts a large population at risk of serious complications related to its use.

Identifiers

PMID33997091
PMCPMC8116012
OpenAlexW3162338201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.