ReviewOrthopaedic journal of sports medicine2021
Comparison of the Sterilization Efficiency of 3 Disinfectants for Dropped Anterior Cruciate Ligament Grafts: A Systematic Review and Meta-analysis.
Review in Orthopaedic journal of sports medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Chlorhexidine as the optimal disinfection method for an accidentally dropped autograft during an anterior cruciate ligament reconstruction surgery: A double-blind study.Journal of experimental orthopaedics · 2026Article
- Anterior Cruciate Ligament Reconstruction: Common Intraoperative Mistakes and Techniques for Error Recovery.Current reviews in musculoskeletal medicine · 2025Review
- Can contaminated musculoskeletal autografts and allografts Be safely and effectively used in Patients? A systematic review.Journal of orthopaedics · 2025Review
- A technical modification to avoid accidental graft drop during hemihamate osteochondral graft harvesting.Journal of hand and microsurgery · 2025Review
- Soaking in Povidone-Iodine, Chlorhexidine, Teicoplanin, Vancomycin, and Saline Solution Differentially Alters Porcine Flexor Tendon Size and Biomechanical Properties.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Effectiveness of a super-oxidized solution for decontaminating ACL grafts: a prospective study.Journal of orthopaedic surgery and research · 2025Article
- Detrimental Effects of Chlorhexidine on Articular Cartilage Viability, Matrix, and Mechanics.The American journal of sports medicine · 2024Article
- What if an articular bone fragment drops on the floor in the course of osteosynthesis? An experimental study.Joint diseases and related surgery · 2024Article
- A Meta-Analysis and Systematic Review ofFoods (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe inadvertent contamination of anterior cruciate ligament (ACL) grafts can occur if they are accidentally dropped on the floor during ACL reconstruction. There has been no meta-analysis conducted to compare the sterilization efficiency of the different disinfectants used on dropped ACL grafts. PURPOSE: To compare the sterilization efficiency of 3 disinfectants to decontaminate ACL grafts as necessary. STUDY
designSystematic review.
methodsA systematic literature review was performed using the MEDLINE, Embase, and Cochrane Library databases. All studies reporting the management of dropped or contaminated grafts were considered for this meta-analysis.
resultsA total of 7 studies meeting inclusion criteria were identified from a literature search. The pooled results of this meta-analysis indicated that the rate of positive cultures of ACL grafts dropped on the operating room floor was 44.9% and that the commonly contaminated microbes were staphylococci and bacilli. The meta-analysis results indicated that the sterilization efficiency of a 4% chlorhexidine solution was superior to an antibiotic solution (odds ratio [OR], 0.17 [95% CI, 0.05-0.57];
conclusionThe results of our meta-analysis demonstrated that staphylococci and bacilli were the most common contaminants on dropped ACL grafts and that decontamination using a 4% chlorhexidine solution more reliably disinfected ACL grafts. This information can help to guide surgeons as regards appropriate remedial measures.
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Registered trials
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