Evidence map›Paper›PMID 33997007›Full record

SynthesisBioMed research international2021

Urinary Angiogenin as a Marker for Bladder Cancer: A Meta-Analysis.

Amir Hossein Aalami, Hossein Abdeahad, Mohammad Mesgari, Thozhukat Sathyapalan, Amirhossein Sahebkar

RetractedOpen access · hybridAbstract readMeta-AnalysisSystematic ReviewRetracted Publication
In one paragraph

Synthesis in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. The role of angiogenin in bladder cancer: where are we in 2025?International urology and nephrology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Amir Hossein AalamiDepartment of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran.ORCID https://orcid.org/0000-0003-4928-254X
Hossein AbdeahadDepartment of Nutrition and Integrative Physiology, Collogue of Health, University of Utah, Salt Lake City, UT, USA.ORCID https://orcid.org/0000-0002-8021-5516
Mohammad MesgariDepartment of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran.ORCID https://orcid.org/0000-0001-5266-5440
Thozhukat SathyapalanAcademic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, UK.
Amirhossein SahebkarBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-8656-1444
Ferdowsi University of Mashhad · IRIslamic Azad University, Mashhad · IRMashhad University of Medical Sciences · IRUniversity of Hull · GBUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBladder cancer (BCa) is a common cancer in North America and Europe that carries considerable morbidity and mortality. A reliable biomarker for early detection of the bladder is crucial for improving the prognosis of BCA. In this meta-analysis, we examine the diagnostic role of the angiogenin (ANG) protein in patients' urine with bladder neoplasm.

methodsWe performed a systematic literature search using ScienceDirect, Web of Science, PubMed/MEDLINE, Scopus, Google Scholar, and Embase, up to 10

resultsFour case-control studies were included with 656 participants (417 cases and 239 controls) in this meta-analysis. The pooled sensitivity of 0.71 (95% CI: 0.66-0.75), specificity of 0.78 (95% CI: 0.73-0.81), LR

conclusionThis meta-analysis showed that ANG could be a fair biomarker for the diagnosis of BCa patients.

Indexed as

Biomarkers, TumorHumansRibonuclease, PancreaticSensitivity and SpecificityUrinary Bladder NeoplasmsangiogeninBiomarkers, TumorRibonuclease, Pancreatic

Identifiers

PMID33997007
PMCPMC8099530
OpenAlexW3159907590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.