Evidence map›Paper›PMID 33997006›Full record

ArticleBioMed research international2021

Experimental Study on the Correlation between miRNA-373 and HIF-1

Chun-Yang Liu, Hisham Al-Ward, Francine Ngaffo Mekontso, Ning Liu, Hui-Qin Zeng, Min Liu, Zi-Rui Yu, Lin Zhang, Yu-Chun Han, Hui Xu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Chun-Yang LiuDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medical Sciences, Jiamusi, China.ORCID https://orcid.org/0000-0001-6817-7337
Hisham Al-WardDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medical Sciences, Jiamusi, China.ORCID https://orcid.org/0000-0003-4087-8275
Francine Ngaffo MekontsoHainan University, Haikou, Hainan Province, China.
Ning LiuDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medical Sciences, Jiamusi, China.
Hui-Qin ZengFirst Affiliated Hospital of Xiamen University, Xiamen 361003, China.
Min LiuBeijing Friendship Hospital, Capital Medical University, Beijing 100000, China.
Zi-Rui YuInner Mongolia Medical University, Hohhot, Inner Mongolia, China.
Lin ZhangJiamusi University, School of Clinical Medicine, Jiamusi, China.
Yu-Chun HanJiamusi University, School of Clinical Medicine, Jiamusi, China.
Hui XuDepartment of Biochemistry and Molecular Biology, Jiamusi University School of Basic Medical Sciences, Jiamusi, China.ORCID https://orcid.org/0000-0001-9651-7634
Jiamusi University · CNAnkang University · CNCapital Medical University · CNFirst Affiliated Hospital of Xiamen University · CNHainan University · CNInner Mongolia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMicroribonucleic acids (miRNAs) have short (approximately 18 to 25) nucleotides and are evolutionarily conserved and endogenously expressed RNAs belonging to a family of noncoding RNA molecules. miRNA-373 regulates cell proliferation, migration, apoptosis, invasion, and repairing damaged DNA after hypoxia stress. Neonatal hypoxic-ischemic encephalopathy (HIE) refers to perinatal asphyxia caused by partial or complete hypoxia, reduced or suspended cerebral blood flow, and fetal or neonatal brain damage. We aim to investigate the relationship between miRNA-373 and HIF-1

methodsHuman (children) samples were divided into four groups (

resultsOur study showed a strong relationship between miRNA-373 and HIF-1

conclusionThe increased change in miRNA-373 expression has a certain diagnostic significance on neonatal HIE. In the occurrence and development of HIE, miRNA-373 is positively correlated with HIF-1

Indexed as

Hypoxia-Ischemia, BrainInfant, Newborn, DiseasesComputational BiologyHumansHypoxia-Inducible Factor 1, alpha SubunitInfant, NewbornMatrix Metalloproteinase 9MicroRNAsVascular Endothelial Growth Factor AHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitMatrix Metalloproteinase 9MicroRNAsMIRN373 microRNA, humanMMP9 protein, humanVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID33997006
PMCPMC8112928
OpenAlexW3159207708

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.