Evidence map›Paper›PMID 33997001›Full record

ArticleBioMed research international2021

Sara Kasirzadeh, Mohammad Hossein Ghahremani, Neda Setayesh, Fereshteh Jeivad, Amir Shadboorestan, Ali Taheri, Abbas Beh-Pajooh, Armin Azadkhah Shalmani, Alireza Ebadollahi-Natanzi, Alamgir Khan and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Study on the mechanism of Shenmai injection in the treatment of sepsis.Journal of cellular and molecular medicine · 2024
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  10. Lipid Fraction fromAntioxidants (Basel, Switzerland) · 2024
    Article
  11. Review
  12. Review
  13. The effect of intraperitoneal LR-PRP on bacterial translocation in an experimental model of peritonitis in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  14. Article
  15. Review
  16. Phytochemical Analysis and Anti-Inflammatory Potential ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Sara KasirzadehDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-8871-4275
Mohammad Hossein GhahremaniDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Neda SetayeshDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy and Biotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Fereshteh JeivadDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Amir ShadboorestanDepartment of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Ali TaheriBiopharmaceutics and Pharmacokinetics Division, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Abbas Beh-PajoohDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Armin Azadkhah ShalmaniDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Alireza Ebadollahi-NatanziMedicinal Plants Department, Imam Khomeini Higher Education Center, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Alamgir KhanAustralian Proteome Analysis Facility (APAF), Level 4, Building F7B, Research Park Drive, Macquarie University, Sydney, NSW 2109, Australia.
Samin SabzevariDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Omid SabzevariDepartment of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-5403-6987
Tehran University of Medical Sciences · IRAGRF Ltd · AUAgricultural Research & Education Organization · IRBiotechnology Research Center · IRTarbiat Modares University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSepsis originates from the host inflammatory response, especially to bacterial infections, and is considered one of the main causes of death in intensive care units. Various agents have been developed to inhibit mediators of the inflammatory response; one prospective agent is

methodsThirty male Wistar rats were divided equally into six groups as follows: sham, CLP, CLP+dexamethasone (DX, 0.2 mg/kg), CLP+

resultsSerum concentrations of IL-1

conclusion

Indexed as

LiverSepsisAnimalsAnti-Inflammatory AgentsCytokinesDisease Models, AnimalInflammationMaleNF-kappa BRatsRats, WistarSignal TransductionSitosterolsAnti-Inflammatory AgentsCytokinesgamma-sitosterolNF-kappa BSitosterols

Identifiers

PMID33997001
PMCPMC8105092
OpenAlexW3159063832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.