Evidence map›Paper›PMID 33996492›Full record

ArticleMolecular genetics and metabolism reports2021

Hyperleucinosis during infections in maple syrup urine disease post liver transplantation.

Laura Guilder, Carlos E Prada, Sofia Saenz, Shailly Jain-Ghai, Natalya Karp, George Mazariegos, Suzanne Ratko, Ramona Salvarinova, Saadet Mercimek-Andrews

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 2 countries.

Laura GuilderDivision of Clinical and Metabolic Genetics, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.
Carlos E PradaDivision of Human Genetics, Cincinnati, Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Sofia SaenzDivision of Human Genetics, Cincinnati, Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Shailly Jain-GhaiDepartment of Medical Genetics, University of Alberta, Stollery Children's Hospital, Alberta Health Services, Edmonton, Alberta, Canada.
Natalya KarpMetabolic Genetics, Western University, Department of Pediatrics, Children's Hospital-London Health Sciences Centre, London, Ontario, Canada.
George MazariegosHillman Center for Pediatric Transplantation, UPMC Children's Hospital of Pittsburgh, Division of Pediatric Transplantation, Department of Surgery, Pittsburgh, PA, USA.
Suzanne RatkoMetabolic Genetics, Western University, Department of Pediatrics, Children's Hospital-London Health Sciences Centre, London, Ontario, Canada.
Ramona SalvarinovaDivision of Biochemical Diseases, Department of Pediatrics, University of British Columbia, BC Children's Hospital, BC Children's Hospital Research Institute, Vancouver, Canada.
Saadet Mercimek-AndrewsDivision of Clinical and Metabolic Genetics, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.
Alberta Health Services · CABritish Columbia Children's Hospital · CAChildren's Hospital of Pittsburgh · USCincinnati Children's Hospital Medical Center · USHospital for Sick Children · CALondon Health Sciences Centre · CAStollery Children's Hospital · CAUniversity of Cincinnati · USWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maple syrup urine disease (MSUD) is due to biallelic variants in one of the three genes:

Indexed as

Branched chain amino acidsHyperleucinosisLiver transplantationMaple syrup urine disease

Identifiers

PMID33996492
PMCPMC8102797
OpenAlexW3158985110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.