Evidence map›Paper›PMID 33996472›Full record

ArticleAsian journal of urology2021

Yuigi Yuminaga, Chris Rothe, Jonathan Kam, Kieran Beattie, Mohan Arianayagam, Chuong Bui, Bertram Canagasingham, Richard Ferguson, Mohamed Khadra, Raymond Ko and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Asian journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Head-to-head comparison ofProstate cancer and prostatic diseases · 2023
    Pooled it
  2. Frontiers in oncology · 2023
    Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yuigi YuminagaNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Chris RotheNepean Radiology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Jonathan KamNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Kieran BeattieNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Mohan ArianayagamNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Chuong BuiNepean Radiology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Bertram CanagasinghamNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Richard FergusonNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Mohamed KhadraNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Raymond KoNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Ken LeNepean Radiology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Diep NguyenNepean Radiology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Celi VarolNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Matthew WinterNepean Urology Research Group, Nepean Hospital, Penrith New South Wales, Australia.
Nepean Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the use of Gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (

methodsWe conducted a review of our prospectively maintained, institutional database to identify 384 patients with post-prostatectomy biochemical failure/recurrence who underwent PSMA PET/CT, CTAP and BS from February 2015 to August 2017 in Nepean Hospital, tertiary referral centre. The results of the three imaging modalities were analysed for their ability to detect local recurrence and distant metastases. PSMA PET/CT and CTAP imaging were separately performed on the same day and the BS was performed within several days (mostly in 24 h). Difference in detection rates was determined between the modalities and the Chi square test was used to determine significance.

resultsA total of 384 patients were identified with a median prostate-specific antigen (PSA) of 0.465 ng/mL (interquartile range =0.19-2.00 ng/mL). Overall, PSMA PET/CT was positive for 245 (63.8%) patients whereas CTAP and BS were positive in 174 patients (45.3%). A total of 98 patients (25.5%) had local or distant metastasis detected on PSMA only, while 20 patients (5.2%) had recurrences detected on CTAP but not on PSMA PET/CT.

conclusionThe use of PSMA PET/CT has a higher detection rate of predicted local or distant metastasis compared to CTAP and BS in the staging of patients with biochemical recurrences after radical prostatectomy.

Indexed as

Bone scanNeoplasm stagingPositron-emission tomographyProstate-specific antigenProstatic neoplasms

Identifiers

PMID33996472
PMCPMC8099644
OpenAlexW3006298413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.