Evidence map›Paper›PMID 33996427›Full record

ArticleMedical mycology case reports2021

The use of posaconazole delayed-release tablets in the successful treatment of suspected mucormycosis in a bottlenose dolphin (

Gonçalo N Marques, Nuno U Silva, Miriam O Leal, Carla A Flanagan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medical mycology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gonçalo N MarquesZoomarine Portugal, N125 KM 65, 8201-864, Guia, Portugal.
Nuno U SilvaZoomarine Portugal, N125 KM 65, 8201-864, Guia, Portugal.
Miriam O LealZoomarine Portugal, N125 KM 65, 8201-864, Guia, Portugal.
Carla A FlanaganZoomarine Portugal, N125 KM 65, 8201-864, Guia, Portugal.
Instituto Português de Malacologia · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucorales infections in cetaceans have a high mortality rate. This case report refers to a bottlenose dolphin calf with suspected mucormycosis treated with posaconazole. This antifungal agent was discontinued after 96 days of therapy, however, the infection relapsed. Posaconazole was then resumed for a total of 255 days, with no signs of disease reactivation. The retrospective analysis of posaconazole serum levels in this successful case showed concentrations varying between 5.18 and 11.63 mg/L.

Indexed as

Bottlenose dolphinCunninghamella bertholettiaeMucormycosisPosaconazoleTherapeutic drug monitoring

Identifiers

PMID33996427
PMCPMC8102706
OpenAlexW3158817460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.