Evidence map›Paper›PMID 33996415›Full record

ArticleActa pharmaceutica Sinica. B2021

Impact of particle size and pH on protein corona formation of solid lipid nanoparticles: A proof-of-concept study.

Wenhao Wang, Zhengwei Huang, Yanbei Li, Wenhua Wang, Jiayu Shi, Fangqin Fu, Ying Huang, Xin Pan, Chuanbin Wu

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
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  16. Exemplifying interspecies variation of liposomeActa pharmaceutica Sinica. B · 2024
    Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenhao WangSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Zhengwei HuangSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Yanbei LiSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Wenhua WangSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Jiayu ShiSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Fangqin FuCollege of Pharmacy, Jinan University, Guangzhou 511443, China.
Ying HuangCollege of Pharmacy, Jinan University, Guangzhou 511443, China.
Xin PanSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.
Chuanbin WuSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When nanoparticles were introduced into the biological media, the protein corona would be formed, which endowed the nanoparticles with new bio-identities. Thus, controlling protein corona formation is critical to

Indexed as

BSA corona-Caused aggregationCell uptakeConformational structureMedium pHNanoparticle-protein interactionProtein coronaSize effectSolid lipid nanoparticles

Identifiers

PMID33996415
PMCPMC8105779

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.