Evidence map›Paper›PMID 33996266›Full record

Trial reportOncoimmunology2021

Poor clinical outcomes and immunoevasive contexture in CXCL13+CD8+ T cells enriched gastric cancer patients.

Kaifeng Jin, Yifan Cao, Yun Gu, Hanji Fang, Yuchao Fei, Jieti Wang, Xin Liu, Kunpeng Lv, Xudong He, Chao Lin and 6 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Oncoimmunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. CD8Cancer science · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Immune Profiling among Colorectal Cancer Subtypes using Dependent Mixture Models.Journal of the American Statistical Association · 2025
    Article
  10. Article
  11. Dysfunction of CD8Cancer science · 2024
    Article
  12. Article
  13. Association betweenWorld journal of gastrointestinal oncology · 2024
    Article
  14. Article
  15. Article
  16. Immunology and immunotherapy in gastric cancer.Clinical and experimental medicine · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Kaifeng JinDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Yifan CaoDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Yun GuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Hanji FangDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Yuchao FeiDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Jieti WangDepartment of Gastric Surgery, Shanghai Cancer Center, Fudan University, Shanghai, China.
Xin LiuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Kunpeng LvDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Xudong HeDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Chao LinDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Hao LiuDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
He LiDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Hongyong HeDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Ruochen LiDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Heng ZhangDepartment of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Jiejie XuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.ORCID 0000-0001-7431-9063
Fudan University · CNSun Yat-sen University · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an adverse survival prognosticator, chemokine (C-X-C motif) ligand 13 (CXCL13) has been studied in several types of malignancies. The secretion and physiological roles of CXCL13 in follicular helper T cells (T

Indexed as

Stomach NeoplasmsCD8-Positive T-LymphocytesChemokine CXCL13Chemotherapy, AdjuvantHumansLymphocytes, Tumor-InfiltratingPrognosisChemokine CXCL13CXCL13 protein, humanadjuvant chemotherapyCXCL13+CD8+ T cellsgastric cancerimmune contextureprognosis

Identifiers

PMID33996266
PMCPMC8081038
OpenAlexW3157154264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.