ArticleBiomedical optics express2021
Strip-based digital image registration for distortion minimization and robust eye motion measurement from scanned ophthalmic imaging systems.
Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Phase diversity improves retinal image quality in adaptive optics scanning light ophthalmoscopy.Biomedical optics express · 2026Article
- Volumetric montaging of optical coherence tomography in human retinas.bioRxiv : the preprint server for biology · 2026Article
- Article
- Phase diversity improves retinal image quality in adaptive optics scanning light ophthalmoscopy.bioRxiv : the preprint server for biology · 2025Article
- Non-uniform signal pooling across the foveola.Current biology : CB · 2025Article
- Sex differences in fixational eye movements following concussion.Journal of vision · 2025Article
- Influence of retinal eccentricity, color blindness, and age on optoretinography measured with AOSLO.Biomedical optics express · 2025Article
- The fundamentals of eye tracking part 4: Tools for conducting an eye tracking study.Behavior research methods · 2025Article
- Multi-spectral autofluorescence variability of the individual retinal pigmented epithelial cells in healthy aging eyes.Scientific reports · 2024Article
- Improved tracking of corneal immune cell dynamics usingBiomedical optics express · 2024Article
- High refresh rate display for natural monocular viewing in AOSLO psychophysics experiments.Optics express · 2024Article
- Are the Hypo-Reflective Clumps Associated With Age-Related Macular Degeneration in Adaptive Optics Ophthalmoscopy Autofluorescent?Investigative ophthalmology & visual science · 2024Article
- Normalized weighted cross correlation for multi-channel image registration.Optics continuum · 2024Article
- Spiral scanning improves subject fixation in widefield retinal imaging.Optics letters · 2024Article
- Comparison between Two Adaptive Optics Methods for Imaging of Individual Retinal Pigmented Epithelial Cells.Diagnostics (Basel, Switzerland) · 2024Article
- Substrip-based registration and automatic montaging of adaptive optics retinal images.Biomedical optics express · 2024Article
- Alignment, calibration, and validation of an adaptive optics scanning laser ophthalmoscope for high-resolution human foveal imaging.Applied optics · 2024Article
- Autofluorescent hyperreflective foci on infrared autofluorescence adaptive optics ophthalmoscopy in central serous chorioretinopathy.American journal of ophthalmology case reports · 2022Article
- Near infrared autofluorescence imaging of retinal pigmented epithelial cells using 663 nm excitation.Eye (London, England) · 2022Article
- Microsaccadic correlates of covert attention and crowding.Journal of vision · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Retinal image-based eye motion measurement from scanned ophthalmic imaging systems, such as scanning laser ophthalmoscopy, has allowed for precise real-time eye tracking at sub-micron resolution. However, the constraints of real-time tracking result in a high error tolerance that is detrimental for some eye motion measurement and imaging applications. We show here that eye motion can be extracted from image sequences when these constraints are lifted, and all data is available at the time of registration. Our approach identifies and discards distorted frames, detects coarse motion to generate a synthetic reference frame and then uses it for fine scale motion tracking with improved sensitivity over a larger area. We demonstrate its application here to tracking scanning laser ophthalmoscopy (TSLO) and adaptive optics scanning light ophthalmoscopy (AOSLO), and show that it can successfully capture most of the eye motion across each image sequence, leaving only between 0.1-3.4% of non-blink frames untracked, while simultaneously minimizing image distortions induced from eye motion. These improvements will facilitate precise measurement of fixational eye movements (FEMs) in TSLO and longitudinal tracking of individual cells in AOSLO.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.