Evidence map›Paper›PMID 33996224›Full record

ArticleBiomedical optics express2021

Multi-scale GCN-assisted two-stage network for joint segmentation of retinal layers and discs in peripapillary OCT images.

Jiaxuan Li, Peiyao Jin, Jianfeng Zhu, Haidong Zou, Xun Xu, Min Tang, Minwen Zhou, Yu Gan, Jiangnan He, Yuye Ling and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
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  4. Text-Driven Weakly Supervised OCT Lesion Segmentation With Structural Guidance.IEEE journal of biomedical and health informatics · 2026
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  18. Effects of Acute Mental Stress on Choroidal Thickness.Bioengineering (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jiaxuan LiJohn Hopcroft Center for Computer Science, Shanghai Jiao Tong University, Shanghai 200240, China.
Peiyao JinDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Jianfeng ZhuDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Haidong ZouDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Xun XuDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Min TangDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.
Minwen ZhouDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai 200080, China.
Yu GanDepartment of Electrical and Computer Engineering, The University of Alabama, AL 35487, USA.ORCID https://orcid.org/0000-0003-3409-3412
Jiangnan HeDepartment of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai 200040, China.
Yuye LingJohn Hopcroft Center for Computer Science, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID https://orcid.org/0000-0002-4628-7604
Yikai SuState Key Lab of Advanced Optical Communication Systems and Networks, Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID https://orcid.org/0000-0002-1526-8187
Shanghai Jiao Tong University · CNShanghai Eye Disease Prevention & Treatment Center · CNUniversity of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the peripapillary region of the retina is complicated and is challenging for segmentation. To address this issue, we develop a novel graph convolutional network (GCN)-assisted two-stage framework to simultaneously label the nine retinal layers and the optic disc. Specifically, a multi-scale global reasoning module is inserted between the encoder and decoder of a U-shape neural network to exploit anatomical prior knowledge and perform spatial reasoning. We conduct experiments on human peripapillary retinal OCT images. We also provide public access to the collected dataset, which might contribute to the research in the field of biomedical image processing. The Dice score of the proposed segmentation network is 0.820 ± 0.001 and the pixel accuracy is 0.830 ± 0.002, both of which outperform those from other state-of-the-art techniques.

Identifiers

PMID33996224
PMCPMC8086482
OpenAlexW3136054725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.