Evidence map›Paper›PMID 33996218›Full record

ReviewBiomedical optics express2021

Photoacoustic-guided surgery from head to toe [Invited].

Alycen Wiacek, Muyinatu A Lediju Bell

Open access · goldAbstract readReview
In one paragraph

Review in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Tracking performance and surgeon assessment of photoacoustic-based surgical guidance methods.International journal of computer assisted radiology and surgery · 2026
    Article
  3. Article
  4. Journal of biomedical optics · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Deep Learning to Localize Photoacoustic Sources in Three Dimensions: Theory and Implementation.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Deep learningJournal of biomedical optics · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alycen WiacekDepartment of Electrical and Computer Engineering, 3400 N. Charles St., Johns Hopkins University, Baltimore, MD 21218, USA.ORCID https://orcid.org/0000-0001-7873-1872
Muyinatu A Lediju BellDepartment of Electrical and Computer Engineering, 3400 N. Charles St., Johns Hopkins University, Baltimore, MD 21218, USA.ORCID https://orcid.org/0000-0002-8394-4482
Johns Hopkins University · US

Funding

A Machine Learning Alternative to Beamforming to Improve Ultrasound Image Quality for Interventional Access to the KidneyR21EB025621 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BELL, MUYINATU A. LEDIJU · 2018 to 2021
$859k
Coherence-Based Photoacoustic Image Guidance of Transsphenoidal SurgeriesR00EB018994 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BELL, MUYINATU A. LEDIJU · 2017 to 2019
$726k
NIBIB NIH HHS R00 EB018994NIBIB NIH HHS R21 EB025621
6 · The paper itself

Abstract

Photoacoustic imaging-the combination of optics and acoustics to visualize differences in optical absorption - has recently demonstrated strong viability as a promising method to provide critical guidance of multiple surgeries and procedures. Benefits include its potential to assist with tumor resection, identify hemorrhaged and ablated tissue, visualize metal implants (e.g., needle tips, tool tips, brachytherapy seeds), track catheter tips, and avoid accidental injury to critical subsurface anatomy (e.g., major vessels and nerves hidden by tissue during surgery). These benefits are significant because they reduce surgical error, associated surgery-related complications (e.g., cancer recurrence, paralysis, excessive bleeding), and accidental patient death in the operating room. This invited review covers multiple aspects of the use of photoacoustic imaging to guide both surgical and related non-surgical interventions. Applicable organ systems span structures within the head to contents of the toes, with an eye toward surgical and interventional translation for the benefit of patients and for use in operating rooms and interventional suites worldwide. We additionally include a critical discussion of complete systems and tools needed to maximize the success of surgical and interventional applications of photoacoustic-based technology, spanning light delivery, acoustic detection, and robotic methods. Multiple enabling hardware and software integration components are also discussed, concluding with a summary and future outlook based on the current state of technological developments, recent achievements, and possible new directions.

Identifiers

PMID33996218
PMCPMC8086464
OpenAlexW3130578334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.