ArticleBiomedical optics express2021
Accuracy of homogeneous models for photon diffusion in estimating neonatal cerebral hemodynamics by TD-NIRS.
Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Anisotropic light propagation in human brain white matter.Neurophotonics · 2025Article
- Cerebral baseline optical and hemodynamic properties in pediatric population: a large cohort time-domain near-infrared spectroscopy study.Neurophotonics · 2024Article
- Effects of red blood cell transfusion on cerebral hemodynamics of preterm neonates.Neurophotonics · 2024Article
- Use of bioresorbable fibers for short-wave infrared spectroscopy using time-domain diffuse optics.Biomedical optics express · 2024Article
- Simulation-based development: shaping clinical procedures for extra-uterine life support technology.Advances in simulation (London, England) · 2023Article
- Article
- Non-invasive estimation ofFrontiers in veterinary science · 2023Article
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Authors and funding
7 authors.
Funding
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Abstract
We assessed the accuracy of homogenous (semi-infinite, spherical) photon diffusion models in estimating absolute hemodynamic parameters of the neonatal brain in realistic scenarios (ischemia, hyperoxygenation, and hypoventilation) from 1.5 cm interfiber distance TD NIRS measurements. Time-point-spread-functions in 29- and 44-weeks postmenstrual age head meshes were simulated by the Monte Carlo method, convoluted with a real instrument response function, and then fitted with photon diffusion models. The results show good accuracy in retrieving brain oxygen saturation, and severe underestimation of total cerebral hemoglobin, suggesting the need for more complex models of analysis or of larger interfiber distances to precisely monitor all hemodynamic parameters.
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