Evidence map›Paper›PMID 33996132›Full record

ArticleRoyal Society open science2021

Characterization of the RNA-interference pathway as a tool for reverse genetic analysis in the nascent phototrophic endosymbiosis,

Benjamin H Jenkins, Finlay Maguire, Guy Leonard, Joshua D Eaton, Steven West, Benjamin E Housden, David S Milner, Thomas A Richards

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Effects of the SymbioticMicroorganisms · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Life Sciences New Talent collection.Royal Society open science · 2022
    Article
  10. Article
  11. Emergent RNA-RNA interactions can promote stability in a facultative phototrophic endosymbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Benjamin H JenkinsLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.ORCID 0000-0002-3803-6418
Finlay MaguireFaculty of Computer Science, Dalhousie University, 6050 University Ave, Halifax, Nova Scotia, Canada B3H 1W5.
Guy LeonardLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.ORCID 0000-0002-4607-2064
Joshua D EatonLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.
Steven WestLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.
Benjamin E HousdenLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.
David S MilnerLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.ORCID 0000-0003-3669-7463
Thomas A RichardsLiving Systems Institute and Biosciences, University of Exeter, Devon EX4 4QD, UK.ORCID 0000-0002-9692-0973
University of Exeter · GBDalhousie University · CA

Funding

Wellcome Trust
6 · The paper itself

Abstract

Endosymbiosis was fundamental for the evolution of eukaryotic complexity. Endosymbiotic interactions can be dissected through forward- and reverse-genetic experiments, such as RNA-interference (RNAi). However, distinguishing small (s)RNA pathways in a eukaryote-eukaryote endosymbiotic interaction is challenging. Here, we investigate the repertoire of RNAi pathway protein-encoding genes in the model nascent endosymbiotic system,

Indexed as

algaedicerinteractionRNAisiRNAsymbiosis

Identifiers

PMID33996132
PMCPMC8059543
OpenAlexW3154462357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.