Evidence map›Paper›PMID 33996105›Full record

ArticleJRSM open2021

The first reported cases of meat allergy following tick bites in the UK.

Rhea A Bansal, Sameer Bahal, Rachael O'Brien, Joanne Miller, Amolak S Bansal, Patrick Fk Yong

Open access · goldAbstract readCase Reports
In one paragraph

Article in JRSM open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Rhea A BansalImmunology Department, Frimley Park Hospital, Frimley Health NHS Trust, Frimley GU16 7UJ, UK.ORCID https://orcid.org/0000-0002-8049-982X
Sameer BahalImmunology Department, The Royal Free Hospital, Royal Free London NHS Foundation Trust, London NW3 2QG, UK.
Rachael O'BrienImmunology Department, Frimley Park Hospital, Frimley Health NHS Trust, Frimley GU16 7UJ, UK.
Joanne MillerImmunology Department, Royal Surrey County Hospital, Royal Surrey NHS Foundation Trust, Surrey GU2 7XX, UK.
Amolak S BansalSt Anthony's Hospital, Cheam, SM3 9DW, UK.
Patrick Fk YongImmunology Department, Frimley Park Hospital, Frimley Health NHS Trust, Frimley GU16 7UJ, UK.ORCID https://orcid.org/0000-0003-1736-2756
Frimley Park Hospital · GBRoyal Surrey County Hospital · GBRoyal Free London NHS Foundation Trust · GBSt. Anthony’s Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic reactions frequently involve the production of immunoglobulin E (IgE) antibodies to proteins. However, reactions directed against carbohydrate moieties are increasingly being recognised. Tick bites can contribute to the development of immunoglobulin E to the galactose-1,3-galactose (alpha-gal) moiety on tick salivary proteins. These IgE molecules can cross-react with alpha-gal found in red meats, causing Type I IgE-mediated hypersensitivity reactions to these foods. We present three cases of delayed reactions to beef, pork and lamb in patients with prior tick bites and in the presence of a positive-specific IgE to alpha-gal. Patients were advised to avoid red meat consumption and to carry emergency treatment in the form of anti-histamines with or without adrenaline autoinjector devices. This is the first published report of red meat allergy caused by tick bites suffered in the UK.

Indexed as

Clinicalimmunology (including allergy)other pathologypathology

Identifiers

PMID33996105
PMCPMC8107943
OpenAlexW3157262157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.